Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Positive Breast Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

4,894

Participants

Timeline

Start Date

October 31, 2004

Primary Completion Date

March 31, 2012

Study Completion Date

June 30, 2016

Conditions
Breast Cancer
Interventions
DRUG

Cyclophosphamide

"Group 1: cyclophosphamide 500 mg/m2 IV every 21 days for 6 cycles~Group 2 and Group 3: cyclophosphamide 600 mg/m2 IV every 14 days for 4 cycles"

DRUG

Docetaxel

75 mg/m2 IV every 21 days for 6 cycles

DRUG

Gemcitabine

2000 mg/m2 IV every 14 days for 4 cycles

DRUG

Paclitaxel

175 mg/m2 IV every 14 days for 4 cycles

DRUG

Doxorubicin

"Group 1: 50 mg/m2 IV every 21 days for 6 cycles~Group 2 and Group 3: 60 mg/m2 IV every 14 days for 4 cycles"

Trial Locations (12)

19118

Chestnut Hill Healthcare Cancer Center, Philadelphia

34994

Robert and Carol Weissman Cancer Center at Martin Memorial, Stuart

35294

Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham

44131

Community Oncology Group at Cleveland Clinic Cancer Center, Independence

58201

Altru Cancer Center at Altru Hospital, Grand Forks

68114

Methodist Estabrook Cancer Center, Omaha

98431

Madigan Army Medical Center - Tacoma, Tacoma

99508

Providence Cancer Center, Anchorage

40536-0093

Lucille P. Markey Cancer Center at University of Kentucky, Lexington

02190

South Shore Hospital, South Weymouth

07601

CCOP - Northern New Jersey, Hackensack

28232-2861

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

NSABP Foundation Inc

NETWORK

NCT00093795 - Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Positive Breast Cancer | Biotech Hunter | Biotech Hunter