174
Participants
Start Date
September 30, 2004
Primary Completion Date
April 30, 2011
Study Completion Date
December 8, 2012
Early Periodontal Treatment
Subjects will receive scaling and root planing at baseline. Three weeks after initiation of the study, they will return and be re-evaluated for the need for periodontal surgery. If indicated, they will then receive definitive periodontal surgery over the next 4 weeks. At the 12-week time point, periodontal surgery will be reevaluated and further therapy provided as needed and make repeated visits as needed to achieve periodontal health.comprehensive periodontal treatment
Usual Dental Hygiene
Subjects will receive routine oral hygiene visits at the 3 and 12-week time points. After a 12-week period (24 week time point) to allow healing and resolution of a systemic inflammatory state, patients will return for follow-up measurements of periodontal parameters, vascular function and inflammation.
Boston University Medical Campus, Boston
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Boston University
OTHER