Impact of Gum Infection on Heart Disease

NACompletedINTERVENTIONAL
Enrollment

174

Participants

Timeline

Start Date

September 30, 2004

Primary Completion Date

April 30, 2011

Study Completion Date

December 8, 2012

Conditions
Cardiovascular DiseasePeriodontal Disease
Interventions
PROCEDURE

Early Periodontal Treatment

Subjects will receive scaling and root planing at baseline. Three weeks after initiation of the study, they will return and be re-evaluated for the need for periodontal surgery. If indicated, they will then receive definitive periodontal surgery over the next 4 weeks. At the 12-week time point, periodontal surgery will be reevaluated and further therapy provided as needed and make repeated visits as needed to achieve periodontal health.comprehensive periodontal treatment

PROCEDURE

Usual Dental Hygiene

Subjects will receive routine oral hygiene visits at the 3 and 12-week time points. After a 12-week period (24 week time point) to allow healing and resolution of a systemic inflammatory state, patients will return for follow-up measurements of periodontal parameters, vascular function and inflammation.

Trial Locations (1)

02118

Boston University Medical Campus, Boston

All Listed Sponsors
collaborator

National Institute of Dental and Craniofacial Research (NIDCR)

NIH

lead

Boston University

OTHER

NCT00093236 - Impact of Gum Infection on Heart Disease | Biotech Hunter | Biotech Hunter