Preventing Sexual Transmission of HIV With Anti-HIV Drugs

PHASE3CompletedINTERVENTIONAL
Enrollment

3,526

Participants

Timeline

Start Date

February 28, 2005

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
HIV Infections
Interventions
DRUG

Atazanavir

300 mg taken orally once daily

DRUG

Didanosine

400 mg taken orally once daily

DRUG

Efavirenz

600 mg taken orally once daily

DRUG

Emtricitabine/Tenofovir disoproxil fumarate

200 mg emtricitabine/ 300 mg tenofovir disoproxil fumarate tablet taken orally once daily

DRUG

Lamivudine

300 mg taken orally once daily

DRUG

Lopinavir/Ritonavir

200 mg lopinavir/ 50 mg ritonavir tablet taken orally once daily

DRUG

Nevirapine

200 mg taken orally once daily for 14 days followed by 200 mg taken orally twice daily

DRUG

Stavudine

Dosage depends on weight

DRUG

Tenofovir disoproxil fumarate

300 mg taken orally once daily

DRUG

Zidovudine/Lamivudine

150 mg lamivudine/ 300 mg zidovudine tablet taken orally twice daily

Trial Locations (17)

2001

Soweto HPTN CRS, Johannesburg

2092

Wits Helen Joseph Hospital CRS (Wits HJH CRS), Johannesburg

40100

Kisumu Crs, Kisumu

50202

CMU HIV Prevention CRS, Chiang Mai

411002

NARI Clinic at Gadikhana Dr. Kotnis Municipal Dispensary CRS, Pune

411011

NARI Clinic at NIV CRS, Pune

411026

NARI Pune CRS, Pune

600113

Chennai Antiviral Research and Treatment (CART) CRS, Chennai

02115

Fenway Community Health Ctr. CRS, Boston

Unknown

Gaborone CRS, Gaborone

Blantyre CRS, Blantyre

Malawi CRS, Lilongwe

Parirenyatwa CRS, Harare

26030-380

Hospital Geral de Nova Iguaçu CRS (HGNI CRS), Nova Iguaçu

91350 200

Hospital Nossa Senhora da Conceicao CRS, Port Alegre

20221-903

HSE-Hospital dos Servidores do Estado CRS, Rio de Janeiro

21040-360

Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS, Rio de Janeiro

All Listed Sponsors
collaborator

HIV Prevention Trials Network

NETWORK

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00074581 - Preventing Sexual Transmission of HIV With Anti-HIV Drugs | Biotech Hunter | Biotech Hunter