Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

PHASE3CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 16, 2007

Primary Completion Date

February 1, 2013

Study Completion Date

June 30, 2021

Conditions
Intraocular Retinoblastoma
Interventions
DRUG

liposomal vincristine sulfate

Given IV

PROCEDURE

cryosurgery

Application of extreme cold to destroy abnormal or diseased tissue.

PROCEDURE

laser surgery

Surgery using a laser (instead of a scalpel) to cut tissue

DRUG

carboplatin

Given IV

DRUG

etoposide

Given IV

BIOLOGICAL

filgrastim

Given subcutaneously

Trial Locations (11)

20057

Lombardi Comprehensive Cancer Center at Georgetown University, Washington D.C.

27710

Duke University Medical Center, Durham

30322

Children's Healthcare of Atlanta - Egleston, Atlanta

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

60612

University of Illinois, Chicago

77030

Baylor College of Medicine, Houston

M D Anderson Cancer Center, Houston

90027

Children's Hospital Los Angeles, Los Angeles

90242

Southern California Permanente Medical Group, Downey

91006-3776

Children's Oncology Group, Arcadia

06520-8032

Yale University, New Haven

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00072384 - Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma | Biotech Hunter | Biotech Hunter