Gemcitabine and Vinorelbine in Treating Young Patients With Recurrent or Refractory Hodgkin's Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

July 31, 2004

Primary Completion Date

September 30, 2007

Conditions
Lymphoma
Interventions
BIOLOGICAL

filgrastim

Given by mouth or IV, 5 micrograms/kg/dose (up to 10 micrograms/kg/dose) daily starting on day 9 for a minimum of 7 days and until the ANC is greater to or equal to 1,500/uL.

DRUG

gemcitabine hydrochloride

Given IV over 100 minutes dose 1000 mg/m2/dose in 500 ml NS on days 1 and 8

DRUG

vinorelbine tartrate

Given IV over 6-10 minutes (central venous catheter). Dose 25 mg/m2/dose on days 1 and 8

Trial Locations (123)

1205

Swiss Pediatric Oncology Group Geneva, Geneva

6001

Princess Margaret Hospital for Children, Perth

10032

Herbert Irving Comprehensive Cancer Center at Columbia University, New York

10461

Albert Einstein Cancer Center at Albert Einstein College of Medicine, The Bronx

10595

New York Medical College, Valhalla

13210

SUNY Upstate Medical University Hospital, Syracuse

14642

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester

15213

Children's Hospital of Pittsburgh, Pittsburgh

19899

Alfred I. duPont Hospital for Children, Wilmington

20007

Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington D.C.

21215

Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore

25302

West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division, Charleston

27710

Duke Comprehensive Cancer Center, Durham

29605

Greenville Hospital System Cancer Center, Greenville

30322

Winship Cancer Institute of Emory University, Atlanta

32207

Nemours Children's Clinic, Jacksonville

32504

Sacred Heart Cancer Center at Sacred Heart Hospital, Pensacola

32806

Nemours Children's Clinic - Orlando, Orlando

33136

University of Miami Sylvester Comprehensive Cancer Center, Miami

33155

Miami Children's Hospital, Miami

33407

Kaplan Cancer Center at St. Mary's Medical Center, West Palm Beach

33607

St. Joseph's Cancer Institute at St. Joseph's Hospital, Tampa

33701

All Children's Hospital, St. Petersburg

33901

Lee Cancer Care of Lee Memorial Health System, Fort Myers

35294

Lurleen Wallace Comprehensive Cancer at University of Alabama-Birmingham, Birmingham

37403

T.C. Thompson Children's Hospital, Chattanooga

37916

East Tennessee Children's Hospital, Knoxville

38105

St. Jude Children's Research Hospital, Memphis

40232

Kosair Children's Hospital, Louisville

44501

Tod Children's Hospital, Youngstown

46260

St. Vincent Indianapolis Hospital, Indianapolis

48236

Van Elslander Cancer Center at St. John Hospital and Medical Center, Grosse Pointe Woods

48503

Hurley Medical Center, Flint

48910

Breslin Cancer Center at Ingham Regional Medical Center, Lansing

50309

Blank Children's Hospital, Des Moines

53226

Midwest Children's Cancer Center, Milwaukee

54449

Marshfield Clinic - Marshfield Center, Marshfield

55404

Children's Hospitals and Clinics of Minneapolis, Minneapolis

55455

University of Minnesota Medical Center & Children's Hospital - Fairview, Minneapolis

60614

Children's Memorial Hospital - Chicago, Chicago

63110

Siteman Cancer Center at Barnes-Jewish Hospital, St Louis

64108

Children's Mercy Hospital, Kansas City

72205

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock

73104

Oklahoma University Cancer Institute, Oklahoma City

75230

Medical City Dallas Hospital, Dallas

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

76508

CCOP - Scott and White Hospital, Temple

78207

University of Texas Health Science Center at San Antonio, San Antonio

78466

Driscoll Children's Hospital, Corpus Christi

79106

Texas Tech University Health Sciences Center School of Medicine - Amarillo, Amarillo

79410

Covenant Children's Hospital, Lubbock

92354

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda

94115

UCSF Comprehensive Cancer Center, San Francisco

94305

Stanford Comprehensive Cancer Center - Stanford, Stanford

95813

Cancer Research Center of Hawaii, Honolulu

95825

Kaiser Permanente Medical Center - Oakland, Sacramento

97227

Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland

98405

Mary Bridge Children's Hospital and Health Center - Tacoma, Tacoma

98431

Madigan Army Medical Center - Tacoma, Tacoma

90242-2814

Southern California Permanente Medical Group, Downey

90095-1781

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles

93638-8762

Children's Hospital Central California, Madera

92123-4282

Children's Hospital and Health Center - San Diego, San Diego

06360-2875

Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center, Farmington

32610-0232

University of Florida Shands Cancer Center, Gainesville

32803-1273

Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando

31403-3089

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center, Savannah

62794-9620

Southern Illinois University School of Medicine, Springfield

46202-5289

Indiana University Cancer Center, Indianapolis

66160-7357

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center, Kansas City

40536-0293

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington

04401

CancerCare of Maine at Eastern Maine Medial Center, Bangor

04074-9308

Maine Children's Cancer Program, Scarborough

21231-2410

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

02111

Floating Hospital for Children at Tufts - New England Medical Center, Boston

02115

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston

01655

UMASS Memorial Cancer Center - University Campus, Worcester

48109-0238

C.S. Mott Children's Hospital at University of Michigan Medical Center, Ann Arbor

48201-1379

Barbara Ann Karmanos Cancer Institute, Detroit

49503-2560

Spectrum Health Hospital - Butterworth Campus, Grand Rapids

39216-4505

University of Mississippi Medical Center, Jackson

07601

Hackensack University Medical Center Cancer Center, Hackensack

07039

St. Barnabas Medical Center Cancer Center, Livingston

07962

Overlook Hospital, Morristown

07112

Newark Beth Israel Medical Center, Newark

87131-5636

University of New Mexico Cancer Research and Treatment Center, Albuquerque

12208-3419

Albany Medical Center Hospital, Albany

11201-5493

Brooklyn Hospital Center, Brooklyn

14263-0001

Roswell Park Cancer Institute, Buffalo

28232-2861

Blumenthal Cancer Center at Carolinas Medical Center, Charlotte

28233-3549

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte

44308-1062

Children's Hospital Medical Center of Akron, Akron

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

44106-5000

Rainbow Babies and Children's Hospital, Cleveland

44195-5217

Cleveland Clinic Taussig Cancer Center, Cleveland

45404-1815

Children's Medical Center - Dayton, Dayton

17822-0001

Geisinger Medical Center, Danville

17033-0850

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey

19104-9786

Children's Hospital of Philadelphia, Philadelphia

19134-1095

St. Christopher's Hospital for Children, Philadelphia

02903

Rhode Island Hospital Comprehensive Cancer Center, Providence

57117-5039

Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls

37232-6310

Vanderbilt-Ingram Cancer Center, Nashville

76104-9958

Cook Children's Medical Center - Fort Worth, Fort Worth

77030-2399

Baylor University Medical Center - Houston, Houston

78229-3993

Methodist Children's Hospital of South Texas, San Antonio

84113-1100

Primary Children's Medical Center, Salt Lake City

23507-1971

Children's Hospital of The King's Daughters, Norfolk

99220-2555

Providence Cancer Center at Sacred Heart Medical Center, Spokane

54307-3508

St. Vincent Hospital Regional Cancer Center, Green Bay

T6G 1Z2

University of Alberta Hospital, Edmonton

J1H5N4

CHUS-Hopital Fleurimont, Sherbrooke

V6H 3V4

Children's & Women's Hospital of British Columbia, Vancouver

R3E 0V9

CancerCare Manitoba, Winnipeg

B3K 6R8

IWK Health Centre, Halifax

L8N 3Z5

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton

K1H 8L1

Children's Hospital of Eastern Ontario, Ottawa

M5G 1X8

Hospital for Sick Children, Toronto

H3H 1P3

Montreal Children's Hospital at McGill University Health Center, Montreal

H3T 1C5

Hopital Sainte Justine, Montreal

S7N 4H4

Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon

G1V 4G2

Centre Hospitalier Universitaire de Quebec, Québec

00912

San Jorge Children's Hospital, Santurce

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00070304 - Gemcitabine and Vinorelbine in Treating Young Patients With Recurrent or Refractory Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter