NCT00068341 - Docetaxel and Carboplatin With or Without Trastuzumab Before Surgery in Treating Women With Locally Advanced Breast Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2003

Primary Completion Date

November 30, 2013

Study Completion Date

November 30, 2013

Conditions

Breast Cancer

Interventions

BIOLOGICAL

trastuzumab

Cycle 5-7 post-op only Day 1 4mg/kg IV Day 8, 15 2mg/kg IV Cycle 8 Cycle 8 Day 1, 8, 15 2mg/kg IV Day 22 6mg/kg IV

DRUG

carboplatin

Cycle 1-8 Day 1 or 2 AUC = 6 IV

DRUG

docetaxel

Cycle 1-8 Day 1 or 2: 75 mg/m2 IV

BIOLOGICAL

trastuzumab

"Cycle 1-4 pre-op Day 1 4mg/kg IV Day 8, 15 2mg/kg IV~Cycle 5-7 post-op Day 1 4mg/kg IV Day 8, 15 2mg/kg IV~Cycle 8 Day 1, 8, 15 2mg/kg IV Day 22 6mg/kg IV"

Trial Locations (4)

72205

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock

90089-9181

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles

90095-1781

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles

91767-3021

Wilshire Oncology Medical Group, Incorporated - Pomona, Pomona