4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?

PHASE2CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 30, 2001

Primary Completion Date

October 31, 2003

Study Completion Date

October 31, 2003

Conditions
Alpha 1-Antitrypsin Deficiency
Interventions
DRUG

4-PBA

During the first 3 days of this phase baseline serum AAT levels will be determined. The participants will be then given increased amounts of 4-PBA orally in 6 divided doses (day 4-6, 30 g/day and day 7-9, 40/day

Trial Locations (1)

32610

University of Florida, Gainesville

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Alpha-1 Foundation

OTHER

collaborator

Brantly, Mark L., M.D.

INDIV

lead

University of Florida

OTHER

NCT00067756 - 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency? | Biotech Hunter | Biotech Hunter