371
Participants
Start Date
September 30, 1992
Primary Completion Date
January 31, 1994
Study Completion Date
April 30, 1994
Dexamethasone Early
Tapering course of dexamethasone in doses given twice a day (0.25 mg per kilogram of body weight per dose for five days, then 0.15 mg, 0.07 mg, and 0.03 mg per kilogram per dose for three days each), followed by two weeks of saline.
Dexamethasone Late
Saline for two weeks, followed by either the same tapering two-week course of dexamethasone given to the first group, if the respiratory-index score was \>=2.4 on treatment day 14, or an additional two weeks of saline
George Washington University, Washington D.C.
Emory University, Atlanta
University of Miami, Miami
University of Tennessee, Memphis
Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland
Cincinnati Children's Medical Center, Cincinnati
Indiana University, Indianapolis
Wayne State University, Detroit
University of Texas Southwestern Medical Center at Dallas, Dallas
University of New Mexico, Albuquerque
Stanford University, Palo Alto
Yale University, New Haven
Brown University, Women & Infants Hospital of Rhode Island, Providence
National Center for Research Resources (NCRR)
NIH
NICHD Neonatal Research Network
NETWORK