Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers

PHASE2CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

September 30, 1997

Primary Completion Date

December 31, 2002

Study Completion Date

February 28, 2005

Conditions
Skin UlcersSickle Cell Anemia
Interventions
DRUG

Arginine Butyrate

To determine if Arginine Butyrate accelerates healing of refractory leg ulcers over Standard Local Care alone.

OTHER

Standard local care dressing

To heal leg ulcers.

Trial Locations (4)

10029

Mount Sinai School of Medicine, New York

38103

University of Tennessee, Memphis Cancer Center, Memphis

60612

University of Illinois College of Medicine, Chicago

02118

Boston University School of Medicine, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Boston Medical Center

OTHER

collaborator

University of Illinois at Chicago

OTHER

collaborator

Icahn School of Medicine at Mount Sinai

OTHER

collaborator

University of Tennessee

OTHER

collaborator

Schneider Children's Medical Center, Israel

OTHER

lead

Susan P. Perrine

OTHER