Radiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Lymphoma or Waldenstrom's Macroglobulinemia

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

February 28, 1998

Primary Completion Date

May 31, 2001

Conditions
LeukemiaLymphoma
Interventions
BIOLOGICAL

filgrastim

as prescribed by physician

PROCEDURE

autologous bone marrow transplantation

1-2 weeks before treatment

PROCEDURE

peripheral blood stem cell transplantation

1-2 weeks before treatment

RADIATION

indium In 111 monoclonal antibody MN-14

intravenous infusion over 30 min; single dose

RADIATION

yttrium Y 90 epratuzumab

intravenous infusion over 30 min; single dose

Trial Locations (4)

19104

University of Pennsylvania Cancer Center, Philadelphia

07103

Garden State Cancer Center, Belleville

07039

St. Barnabas Medical Center, Livingston

07503

St. Joseph's Hospital and Medical Center, Paterson

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Garden State Cancer Center at the Center for Molecular Medicine and Immunology

OTHER

NCT00004107 - Radiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Lymphoma or Waldenstrom's Macroglobulinemia | Biotech Hunter | Biotech Hunter