Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

PHASE3CompletedINTERVENTIONAL

Enrollment

277

Participants

Timeline

Start Date

March 31, 1999

Primary Completion Date

October 31, 2007

Conditions

Childhood HepatoblastomaRecurrent Childhood Liver CancerStage I Childhood Liver Cancer

Interventions

PROCEDURE

therapeutic conventional surgery

Undergo surgical resection

DRUG

cisplatin

Given IV

DRUG

vincristine sulfate

Given IV

DRUG

fluorouracil

Given IV

DRUG

amifostine trihydrate

Given IV

DRUG

carboplatin

Given IV

Trial Locations (1)

Children's Oncology Group, Arcadia

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00003994 - Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer | Biotech Hunter | Biotech Hunter