Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

PHASE1/PHASE2CompletedINTERVENTIONAL
Timeline

Start Date

February 28, 1998

Study Completion Date

April 30, 2004

Conditions
Chronic Myeloproliferative DisordersLeukemiaMyelodysplastic SyndromesThrombocytopenia
Interventions
BIOLOGICAL

filgrastim

DIETARY_SUPPLEMENT

vitamin E

DRUG

busulfan

DRUG

cytarabine

DRUG

etoposide

DRUG

fludarabine phosphate

DRUG

isotretinoin

DRUG

topotecan hydrochloride

PROCEDURE

bone marrow ablation with stem cell support

PROCEDURE

peripheral blood stem cell transplantation

Trial Locations (2)

19129

Medical College of Pennsylvania Hospital, Philadelphia

Medical College of Pennsylvania, Philadelphia

All Listed Sponsors
lead

Drexel University College of Medicine

OTHER

NCT00003619 - Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia | Biotech Hunter | Biotech Hunter