Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

370

Participants

Timeline

Start Date

October 31, 1998

Primary Completion Date

August 31, 2005

Study Completion Date

May 14, 2018

Conditions
Brain and Central Nervous System Tumors
Interventions
DRUG

lomustine

DRUG

procarbazine hydrochloride

DRUG

vincristine sulfate

RADIATION

radiation therapy

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

SWOG Cancer Research Network

NETWORK

collaborator

North Central Cancer Treatment Group

NETWORK

collaborator

Eastern Cooperative Oncology Group

NETWORK

collaborator

NRG Oncology

OTHER

lead

Radiation Therapy Oncology Group

NETWORK