NCT00003204View on ClinicalTrials.gov

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Low-Grade Non-Hodgkin's Lymphoma

PHASE3CompletedINTERVENTIONAL

Enrollment

515

Participants

Timeline

Start Date

March 31, 1998

Primary Completion Date

May 31, 2006

Conditions

Stage III Grade 1 Follicular LymphomaStage III Grade 2 Follicular LymphomaStage III Grade 3 Follicular LymphomaStage III Small Lymphocytic LymphomaStage IV Grade 1 Follicular LymphomaStage IV Grade 2 Follicular LymphomaStage IV Grade 3 Follicular LymphomaStage IV Small Lymphocytic Lymphoma

Interventions

DRUG

cyclophosphamide

Given IV

DRUG

fludarabine phosphate

Given IV

DRUG

vincristine sulfate

Given IV

DRUG

prednisone

Given PO

BIOLOGICAL

rituximab

Given IV

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

02215

Eastern Cooperative Oncology Group, Boston

All Listed Sponsors

lead

National Cancer Institute (NCI)

NIH

NCT00003204 - Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Low-Grade Non-Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter