Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

March 26, 1997

Primary Completion Date

May 31, 2000

Conditions
Colorectal CancerDiarrhea
Interventions
DRUG

loperamide hydrochloride

DRUG

octreotide acetate

Trial Locations (33)

10021

Memorial Sloan-Kettering Cancer Center, New York

New York Presbyterian Hospital - Cornell Campus, New York

10029

Mount Sinai Medical Center, NY, New York

11030

CCOP - North Shore University Hospital, Manhasset

North Shore University Hospital, Manhasset

13210

CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., Syracuse

State University of New York - Upstate Medical University, Syracuse

19899

CCOP - Christiana Care Health Services, Wilmington

21201

Marlene & Stewart Greenebaum Cancer Center, University of Maryland, Baltimore

27710

Duke Comprehensive Cancer Center, Durham

33140

CCOP - Mount Sinai Medical Center, Miami Beach

38163

University of Tennessee, Memphis Cancer Center, Memphis

52242

University of Iowa Hospitals and Clinics, Iowa City

55455

University of Minnesota Cancer Center, Minneapolis

60612

University of Illinois at Chicago Health Sciences Center, Chicago

60637

University of Chicago Cancer Research Center, Chicago

63110

Barnes-Jewish Hospital, St Louis

65203

Ellis Fischel Cancer Center - Columbia, Columbia

89106

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas

92093-0658

University of California San Diego Cancer Center, La Jolla

94115-0128

UCSF Cancer Center and Cancer Research Institute, San Francisco

20307-5000

Walter Reed Army Medical Center, Washington D.C.

02115

Dana-Farber Cancer Institute, Boston

01655

University of Massachusetts Memorial Medical Center, Worcester

68198-3330

University of Nebraska Medical Center, Omaha

03756

Norris Cotton Cancer Center, Lebanon

27599-7295

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill

27104-4241

CCOP - Southeast Cancer Control Consortium, Winston-Salem

27157-1082

Comprehensive Cancer Center of Wake Forest University Baptist Medical Center, Winston-Salem

02903

Rhode Island Hospital, Providence

29425-0721

Medical University of South Carolina, Charleston

05401-3498

Vermont Cancer Center, Burlington

23298-0037

MBCCOP - Massey Cancer Center, Richmond

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

SWOG Cancer Research Network

NETWORK

collaborator

Cancer and Leukemia Group B

NETWORK

lead

Eastern Cooperative Oncology Group

NETWORK