120
Participants
Start Date
December 31, 1996
Primary Completion Date
November 30, 2002
Study Completion Date
April 30, 2006
cytarabine
Given IV
dexamethasone
Given IV
etoposide
Given IV
idarubicin
Given IV
ifosfamide
Given IV
leucovorin calcium
mesna
Given IV
pegaspargase
Given IV
therapeutic hydrocortisone
thioguanine
vincristine sulfate
Given IV
low-LET cobalt-60 gamma ray therapy
low-LET electron therapy
low-LET photon therapy
Methotrexate
Given IV
Princess Margaret Hospital for Children, Perth
Kaplan Cancer Center, New York
Memorial Sloan-Kettering Cancer Center, New York
Herbert Irving Comprehensive Cancer Center, New York
Children's Hospital of Pittsburgh, Pittsburgh
Children's Hospital of Philadelphia, Philadelphia
University of Iowa Hospitals and Clinics, Iowa City
University of Wisconsin Comprehensive Cancer Center, Madison
University of Minnesota Cancer Center, Minneapolis
Mayo Clinic Cancer Center, Rochester
University of Chicago Cancer Research Center, Chicago
Children's Mercy Hospital - Kansas City, Kansas City
Children's Hospital of Denver, Denver
Huntsman Cancer Institute, Salt Lake City
Long Beach Memorial Medical Center, Long Beach
Children's Hospital of Orange County, Orange
Children's Hospital and Regional Medical Center - Seattle, Seattle
Fred Hutchinson Cancer Research Center, Seattle
Children's Hospital Los Angeles, Los Angeles
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles
UCSF Cancer Center and Cancer Research Institute, San Francisco
Children's National Medical Center, Washington D.C.
Indiana University Cancer Center, Indianapolis
University of Michigan Comprehensive Cancer Center, Ann Arbor
University of Nebraska Medical Center, Omaha
Lineberger Comprehensive Cancer Center, UNC, Chapel Hill
Children's Hospital Medical Center - Cincinnati, Cincinnati
Ireland Cancer Center, Cleveland
Children's Hospital of Columbus, Columbus
Doernbecher Children's Hospital, Portland
Vanderbilt Cancer Center, Nashville
British Columbia Children's Hospital, Vancouver
IWK Grace Health Centre, Halifax
National Cancer Institute (NCI)
NIH
Children's Oncology Group
NETWORK