Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

PHASE3CompletedINTERVENTIONAL
Enrollment

2,078

Participants

Timeline

Start Date

September 30, 1996

Primary Completion Date

March 31, 2006

Conditions
Leukemia
Interventions
DRUG

asparaginase

Given IV

DRUG

cyclophosphamide

Given IV

DRUG

cytarabine

Given IV

DRUG

daunorubicin hydrochloride

Given IV

DRUG

dexamethasone

Given IV

DRUG

doxorubicin hydrochloride

Given IV

DRUG

idarubicin

Given IV

DRUG

mercaptopurine

Given IV

DRUG

methotrexate

Given PO

DRUG

pegaspargase

Given IV

DRUG

prednisone

Given PO

DRUG

thioguanine

Given IV

DRUG

vincristine sulfate

Given IV

RADIATION

radiation therapy

Trial Locations (35)

6001

Princess Margaret Hospital for Children, Perth

10016

NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York

10021

Memorial Sloan-Kettering Cancer Center, New York

10029

Mount Sinai School of Medicine, New York

10032

Herbert Irving Comprehensive Cancer Center, New York

15213

Children's Hospital of Pittsburgh, Pittsburgh

19104

Children's Hospital of Philadelphia, Philadelphia

55455

University of Minnesota Cancer Center, Minneapolis

55905

Mayo Clinic Cancer Center, Rochester

64108

Children's Mercy Hospital, Kansas City

80218

Children's Hospital of Denver, Denver

90806

Long Beach Memorial Medical Center, Long Beach

92868

Children's Hospital of Orange County, Orange

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

90027-0700

Children's Hospital Los Angeles, Los Angeles

90095-1781

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles

94143-0128

UCSF Cancer Center and Cancer Research Institute, San Francisco

20010-2970

Children's National Medical Center, Washington D.C.

60637-1470

University of Chicago Cancer Research Center, Chicago

46202-5289

Indiana University Cancer Center, Indianapolis

52242-1009

Holden Comprehensive Cancer Center at The University of Iowa, Iowa City

48109-0752

University of Michigan Comprehensive Cancer Center, Ann Arbor

68198-3330

University of Nebraska Medical Center, Omaha

08901-1780

Saint Peter's University Hospital, New Brunswick

27599-7295

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill

45229-3039

Children's Hospital Medical Center - Cincinnati, Cincinnati

44106-5065

Ireland Cancer Center, Cleveland

43205-2696

Children's Hospital of Columbus, Columbus

97201-3098

Doernbecher Children's Hospital, Portland

37232-6838

Vanderbilt-Ingram Cancer Center, Nashville

77030-4009

University of Texas - MD Anderson Cancer Center, Houston

98109-1024

Fred Hutchinson Cancer Research Center, Seattle

53792-6164

University of Wisconsin Comprehensive Cancer Center, Madison

V6H 3V4

British Columbia Children's Hospital, Vancouver

B3J 3G9

IWK Health Centre, Halifax

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00002812 - Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia | Biotech Hunter | Biotech Hunter