Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma

PHASE3CompletedINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

July 31, 1990

Study Completion Date

September 30, 2003

Conditions
Neuroblastoma
Interventions
DRUG

carboplatin

DRUG

cisplatin

DRUG

cyclophosphamide

DRUG

dacarbazine

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

ifosfamide

DRUG

melphalan

DRUG

mesna

DRUG

vincristine sulfate

DRUG

vindesine

PROCEDURE

autologous bone marrow transplantation

PROCEDURE

conventional surgery

RADIATION

low-LET cobalt-60 gamma ray therapy

RADIATION

low-LET electron therapy

RADIATION

low-LET photon therapy

RADIATION

radioisotope therapy

Trial Locations (1)

DOH-5-0226

University of Cologne, Frechen

All Listed Sponsors
lead

Children's Hospital Medical Center, Cincinnati

OTHER