Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma

PHASE3UnknownINTERVENTIONAL
Enrollment

750

Participants

Timeline

Start Date

September 30, 1994

Conditions
Multiple Myeloma and Plasma Cell Neoplasm
Interventions
BIOLOGICAL

filgrastim

BIOLOGICAL

recombinant interferon alfa

BIOLOGICAL

sargramostim

DRUG

carmustine

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

melphalan

DRUG

methylprednisolone

DRUG

prednisone

DRUG

vincristine sulfate

RADIATION

low-LET cobalt-60 gamma ray therapy

RADIATION

low-LET photon therapy

Trial Locations (1)

LS1 3EX

Leeds Teaching Hospital Trust, Leeds

Sponsors
All Listed Sponsors
lead

Medical Research Council

OTHER_GOV