Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

6,000

Participants

Timeline

Start Date

June 30, 1993

Study Completion Date

April 30, 2007

Conditions
Breast Cancer
Interventions
DRUG

CMF regimen

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

fluorouracil

DRUG

goserelin acetate

DRUG

leuprolide acetate

DRUG

methotrexate

DRUG

tamoxifen citrate

PROCEDURE

oophorectomy

RADIATION

radiation therapy

Trial Locations (2)

B15 2TT

Cancer Research Campaign Trials Unit-Birmingham (CRCTU), Birmingham

G11 6NT

Beatson Oncology Centre, Glasgow

All Listed Sponsors
collaborator

Cancer Research Campaign Clinical Trials Centre

OTHER

collaborator

Scottish Cancer Therapy Network

OTHER

collaborator

Yorkshire Regional Clinical Trials Research Unit

OTHER

lead

Institute of Cancer Research, United Kingdom

OTHER