Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

Not specified

Conditions
Pneumonia, Pneumocystis CariniiHIV Infections
Interventions
DRUG

Trimetrexate glucuronate

DRUG

Trimethoprim

DRUG

Sulfamethoxazole

DRUG

Dapsone

DRUG

Leucovorin calcium

Trial Locations (1)

90033

Los Angeles County / Health Research Assoc / Drew Med Ctr, Los Angeles

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Jacobus Pharmaceutical

INDUSTRY

lead

U.S. Bioscience

INDUSTRY

NCT00002120 - Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia | Biotech Hunter | Biotech Hunter