A Comparison of Zidovudine Plus Lamivudine Versus ddI Used Alone or in Combination With Zidovudine in HIV-1 Infected Children

PHASE2CompletedINTERVENTIONAL
Enrollment

740

Participants

Timeline

Start Date

Not specified

Primary Completion Date

January 31, 2001

Conditions
HIV Infections
Interventions
DRUG

Lamivudine

DRUG

Zidovudine

DRUG

Didanosine

Trial Locations (91)

10003

Beth Israel Med Ctr / Pediatrics, New York

10016

Bellevue Hosp / New York Univ Med Ctr, New York

10025

Saint Luke's - Roosevelt Hosp Ctr, New York

10029

Metropolitan Hosp Ctr, New York

Mount Sinai Med Ctr / Pediatrics, New York

10032

Columbia Presbyterian Med Ctr, New York

10037

Harlem Hosp Ctr, New York

10457

Bronx Lebanon Hosp Ctr, The Bronx

10595

Westchester Hosp, Valhalla

11021

North Shore Univ Hosp, Great Neck

11040

Schneider Children's Hosp, New Hyde Park

11203

King's County Hosp Ctr / Pediatrics, Brooklyn

SUNY - Brooklyn, Brooklyn

12208

Children's Hosp at Albany Med Ctr, Albany

13210

SUNY Health Sciences Ctr at Syracuse / Pediatrics, Syracuse

14222

Children's Hosp of Buffalo, Buffalo

14642

Univ of Rochester Medical Center, Rochester

20060

Howard Univ Hosp, Washington D.C.

21201

Univ of Maryland at Baltimore / Univ Med Ctr, Baltimore

23507

Senetara Norfolk Gen Hosp, Norfolk

27710

Univ of North Carolina at Chapel Hill / Duke Univ Med Ctr, Durham

29203

Univ of South Carolina School of Med, Columbia

30306

Emory Univ Hosp / Pediatrics, Atlanta

30912

Med College of Georgia, Augusta

31404

Mem Children's Hosp, Savannah

32209

Univ of Florida Health Science Ctr / Pediatrics, Jacksonville

32610

Univ of Florida, Gainesville

32806

Arnold Palmer Hosp for Children & Women, Orlando

33161

Univ of Miami (Pediatric), Miami

33301

Children's Diagnostic and Treatment Ctr of South Florida, Fort Lauderdale

33407

HRS Palm Beach County Public Health Unit, West Palm Beach

33606

Univ of South Florida, Tampa

33614

Saint Joseph's Hosp, Tampa

33701

All Children's Hosp, St. Petersburg

35294

Univ of Alabama at Birmingham Schl of Med / Pediatrics, Birmingham

44106

Case Western Reserve Univ - Pediatric, Cleveland

48201

Children's Hosp of Michigan, Detroit

55455

Univ of Minnesota Med School, Minneapolis

60608

Mount Sinai Hosp Med Ctr, Chicago

60612

Cook County Hosp, Chicago

Univ of Illinois College of Medicine / Pediatrics, Chicago

63110

St Louis Children's Hosp, St Louis

72202

Arkansas Children's Hosp, Little Rock

75235

Children's Med Ctr of Dallas, Dallas

76104

Cook - Fort Worth Children's Med Ctr, Fort Worth

77030

Hermann Hosp / Univ Texas Health Science Ctr, Houston

Texas Children's Hosp / Baylor Univ, Houston

78240

Univ of Texas Health Science Ctr, San Antonio

90033

Los Angeles County - USC Med Ctr, Los Angeles

90801

Long Beach Memorial (Pediatric), Long Beach

117948111

State Univ of New York at Stony Brook, Stony Brook

191044318

Children's Hosp of Philadelphia, Philadelphia

191341095

Saint Christopher's Hosp for Children, Philadelphia

200102916

Children's Hosp of Washington DC, Washington D.C.

212874933

Johns Hopkins Hosp - Pediatric, Baltimore

232980413

Virginia Commonwealth Univ, Richmond

277103499

Duke Univ Med Ctr, Durham

294253312

Med Univ of South Carolina, Charleston

381052794

Saint Jude Children's Research Hosp of Memphis, Memphis

392165405

Univ of Mississippi Med Ctr, Jackson

432052696

Columbus Children's Hosp, Columbus

452292899

Cincinnati Children's Hosp / Univ Hosp, Cincinnati

454041518

Children's Med Ctr, Dayton

606143394

Chicago Children's Memorial Hosp, Chicago

606371470

Univ of Chicago Children's Hosp, Chicago

701122699

Tulane Univ / Charity Hosp of New Orleans, New Orleans

802181088

Children's Hosp of Denver, Denver

900276016

Children's Hosp of Los Angeles/UCLA Med Ctr, Los Angeles

900951752

UCLA Med Ctr / Pediatric, Los Angeles

905022004

Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles

920930672

UCSD Med Ctr / Pediatrics / Clinical Sciences, La Jolla

941430105

UCSF / Moffitt Hosp - Pediatric, San Francisco

943054149

Stanford Univ School of Medicine, Stanford

946091809

Children's Hosp of Oakland, Oakland

958172208

Univ of California / Davis, Sacramento

981050371

Children's Hospital & Medical Center / Seattle ACTU, Seattle

06032

Univ of Connecticut / Farmington, Farmington

06504

Yale Univ Med School, New Haven

021155724

Children's Hosp of Boston, Boston

02118

Boston City Hosp / Pediatrics, Boston

01199

Baystate Med Ctr of Springfield, Springfield

016550001

Univ of Massachusetts Med School, Worcester

089030019

UMDNJ - Robert Wood Johnson Med School / Pediatrics, New Brunswick

071032714

Univ of Medicine & Dentistry of New Jersey / Univ Hosp, Newark

07103

Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl, Newark

071072198

Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl, Newark

02903

Rhode Island Hosp / Brown Univ, Providence

00956

Ramon Ruiz Arnau Univ Hosp / Pediatrics, Bayamón

00680

Mayaguez Med Ctr, Mayagüez

009365067

Univ of Puerto Rico / Univ Children's Hosp AIDS, San Juan

009367344

San Juan City Hosp, San Juan

Sponsors
All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

collaborator

Glaxo Wellcome

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00001066 - A Comparison of Zidovudine Plus Lamivudine Versus ddI Used Alone or in Combination With Zidovudine in HIV-1 Infected Children | Biotech Hunter | Biotech Hunter