The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

1,100

Participants

Timeline

Start Date

Not specified

Study Completion Date

June 30, 1996

Conditions
Mycobacterium Avium-intracellulare InfectionHIV Infections
Interventions
DRUG

Clarithromycin

DRUG

Rifabutin

Trial Locations (42)

10016

NY Univ. HIV/AIDS CRS, New York

10021

Memorial Sloan-Kettering Cancer Ctr., New York

10029

Beth Israel Med. Ctr. (Mt. Sinai), New York

10457

Bronx-Lebanon Hosp. IMPAACT CRS, The Bronx

14215

SUNY - Buffalo, Erie County Medical Ctr., Buffalo

14642

Univ. of Rochester ACTG CRS, Rochester

19104

Hosp. of the Univ. of Pennsylvania CRS, Philadelphia

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia

20059

Howard University Hosp., Div. of Infectious Diseases, ACTU, Washington D.C.

21287

Johns Hopkins Adult AIDS CRS, Baltimore

27401

Regional Center for Infectious Disease, Wendover Medical Center CRS, Greensboro

27599

Unc Aids Crs, Chapel Hill

28203

Carolinas HealthCare System, Carolinas Med. Ctr., Charlotte

33136

Univ. of Miami AIDS CRS, Miami

35294

Alabama Therapeutics CRS, Birmingham

43210

The Ohio State Univ. AIDS CRS, Columbus

44106

Case CRS, Cleveland

44109

MetroHealth CRS, Cleveland

45267

Univ. of Cincinnati CRS, Cincinnati

46202

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis

Methodist Hosp. of Indiana, Indianapolis

52242

Univ. of Iowa Healthcare, Div. of Infectious Diseases, Iowa City

55415

Hennepin County Med. Ctr., Div. of Infectious Diseases, Minneapolis

55455

University of Minnesota, ACTU, Minneapolis

60611

Chicago Children's CRS, Chicago

Northwestern University CRS, Chicago

60612

Cook County Hosp. CORE Ctr., Chicago

Rush Univ. Med. Ctr. ACTG CRS, Chicago

68198

Univ. of Nebraska Med. Ctr., Durham Outpatient Ctr., Omaha

90095

UCLA CARE Center CRS, Los Angeles

94609

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland

96816

Univ. of Hawaii at Manoa, Leahi Hosp., Honolulu

98122

University of Washington AIDS CRS, Seattle

Unknown

Ucsf Aids Crs, San Francisco

St. Louis ConnectCare, Infectious Diseases Clinic, St Louis

Washington U CRS, St Louis

Cornell University A2201, New York

Mbeya Med. Research Program, Mbeya Referral Hosp. CRS, Mbeya

02114

Massachusetts General Hospital ACTG CRS, Boston

02118

Bmc Actg Crs, Boston

02215

Beth Israel Deaconess - East Campus A0102 CRS, Boston

Beth Israel Deaconess Med. Ctr., ACTG CRS, Boston

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00001030 - The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients | Biotech Hunter | Biotech Hunter