Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS

PHASE3CompletedINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

Not specified

Primary Completion Date

July 31, 1991

Conditions
Meningitis, CryptococcalHIV Infections
Interventions
DRUG

Fluconazole

DRUG

Amphotericin B

Trial Locations (28)

10003

Beth Israel Med Ctr / Peter Krueger Clinic, New York

10016

Bellevue Hosp / New York Univ Med Ctr, New York

10021

Cornell Univ Med Ctr, New York

Mem Sloan - Kettering Cancer Ctr, New York

10025

Saint Luke's - Roosevelt Hosp Ctr, New York

10029

Mount Sinai Med Ctr, New York

10465

Jack Weiler Hosp / Bronx Municipal Hosp, The Bronx

10467

Montefiore Med Ctr / Bronx Municipal Hosp, The Bronx

North Central Bronx Hosp / Bronx Municipal Hosp, The Bronx

10468

Bronx Veterans Administration / Mount Sinai Hosp, The Bronx

11373

City Hosp Ctr at Elmhurst / Mount Sinai Hosp, Elmhurst

14215

SUNY / Erie County Med Ctr at Buffalo, Buffalo

14642

Univ of Rochester Medical Center, Rochester

21287

Johns Hopkins Hosp, Baltimore

27710

Duke Univ Med Ctr, Durham

29169

Julio Arroyo, West Columbia

44106

Univ Hosp of Cleveland / Case Western Reserve Univ, Cleveland

70112

Louisiana State Univ School of Medicine, New Orleans

Tulane Univ School of Medicine, New Orleans

90095

UCLA CARE Ctr, Los Angeles

117948153

SUNY - Stony Brook, Stony Brook

275997215

Univ of North Carolina, Chapel Hill

331361013

Univ of Miami School of Medicine, Miami

432101228

Ohio State Univ Hosp Clinic, Columbus

452670405

Holmes Hosp / Univ of Cincinnati Med Ctr, Cincinnati

462025250

Indiana Univ Hosp, Indianapolis

02114

Harvard (Massachusetts Gen Hosp), Boston

02215

Beth Israel Deaconess - West Campus, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Pfizer

INDUSTRY