Safety, Tolerability, and Anti-HIV Activity of DMP 266 (Efavirenz) in Combination With Nelfinavir in HIV-Positive Children

PHASE1CompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

October 31, 1997

Study Completion Date

December 31, 2002

Conditions
HIV Infections
Interventions
DRUG

Nelfinavir mesylate

DRUG

Efavirenz

Trial Locations (27)

10029

Metropolitan Hosp. Ctr., New York

10037

Harlem Hosp. Ctr. NY NICHD CRS, New York

10457

Bronx-Lebanon Hosp. IMPAACT CRS, The Bronx

11203

SUNY Downstate Med. Ctr., Children's Hosp. at Downstate NICHD CRS, Brooklyn

20060

Howard Univ. Washington DC NICHD CRS, Washington D.C.

21201

Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology, Baltimore

32209

Univ. of Florida Jacksonville NICHD CRS, Jacksonville

39213

Univ. of Mississippi Med. Ctr Children's Hosp., Jackson

70112

Tulane/LSU Maternal/Child CRS, New Orleans

90801

Long Beach Memorial Med. Ctr., Miller Children's Hosp., Long Beach

191044318

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia

Unknown

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles

Usc La Nichd Crs, Los Angeles

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland

UCSD Maternal, Child, and Adolescent HIV CRS, San Diego

Harbor - UCLA Med. Ctr. - Dept. of Peds., Div. of Infectious Diseases, Torrance

NYU Med. Ctr., Dept. of Medicine, New York

Nyu Ny Nichd Crs, New York

St. Christopher's Hosp. for Children, Philadelphia

St. Jude/UTHSC CRS, Memphis

Texas Children's Hosp. CRS, Houston

Seattle Children's Hospital CRS, Seattle

UW School of Medicine - CHRMC, Seattle

021155724

HMS - Children's Hosp. Boston, Div. of Infectious Diseases, Boston

016550001

WNE Maternal Pediatric Adolescent AIDS CRS, Worcester

009365067

Univ. of Puerto Rico Ped. HIV/AIDS Research Program CRS, San Juan

009367344

San Juan City Hosp. PR NICHD CRS, San Juan

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00000893 - Safety, Tolerability, and Anti-HIV Activity of DMP 266 (Efavirenz) in Combination With Nelfinavir in HIV-Positive Children | Biotech Hunter | Biotech Hunter