Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

Not specified

Study Completion Date

May 31, 1999

Conditions
Bacterial InfectionsMycosesHIV Infections
Interventions
DRUG

Clarithromycin

DRUG

Rifabutin

DRUG

Sulfamethoxazole-Trimethoprim

DRUG

Dapsone

DRUG

Fluconazole

Trial Locations (2)

98122

University of Washington AIDS CRS, Seattle

Unknown

Ucsf Aids Crs, San Francisco

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH