A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection

PHASE1CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

Not specified

Study Completion Date

February 29, 1996

Conditions
HIV Infections
Interventions
BIOLOGICAL

rgp120/HIV-1MN

BIOLOGICAL

rgp120/HIV-1 SF-2

BIOLOGICAL

gp160 Vaccine (MicroGeneSys)

Trial Locations (34)

10016

NYU Med. Ctr., Dept. of Medicine, New York

10032

Columbia IMPAACT CRS, New York

Incarnation Children's Ctr., New York

11021

North Shore-Long Island Jewish Health System, Dept. of Peds., Great Neck

11203

SUNY Downstate Med. Ctr., Children's Hosp. at Downstate NICHD CRS, Brooklyn

14642

Univ. of Rochester ACTG CRS, Rochester

60612

Cook County Hosp., Chicago

Univ. of Illinois College of Medicine at Chicago, Dept. of Peds., Chicago

77030

Texas Children's Hosp. CRS, Houston

90801

Long Beach Memorial Med. Ctr., Miller Children's Hosp., Long Beach

94110

San Francisco Gen. Hosp., San Francisco

191044318

The Children's Hosp. of Philadelphia IMPAACT CRS, Philadelphia

191341095

St. Christopher's Hosp. for Children, Philadelphia

277103499

DUMC Ped. CRS, Durham

606143394

Univ. of Chicago - Dept. of Peds., Div. of Infectious Disease, Chicago

606371470

Chicago Children's CRS, Chicago

701122699

Tulane/LSU Maternal/Child CRS, New Orleans

900481804

Childrens Hosp. LA - Dept. of Ped., Div. of Clinical Immunology & Allergy, Los Angeles

900951752

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles

905022004

Harbor - UCLA Med. Ctr. - Dept. of Peds., Div. of Infectious Diseases, Torrance

941430105

UCSF Pediatric AIDS CRS, San Francisco

946091809

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland

06032

Univ. of Connecticut Health Ctr., Dept. of Ped., Farmington

06504

Yale Univ. School of Medicine - Dept. of Peds., Div. of Infectious Disease, New Haven

Unknown

Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases, Baltimore

UMDNJ - Robert Wood Johnson, New Brunswick

SUNY Upstate Med. Univ., Dept. of Peds., Syracuse

021155724

HMS - Children's Hosp. Boston, Div. of Infectious Diseases, Boston

02118

BMC, Div. of Ped Infectious Diseases, Boston

01199

Baystate Health, Baystate Med. Ctr., Springfield

016550001

WNE Maternal Pediatric Adolescent AIDS CRS, Worcester

071072198

NJ Med. School CRS, Newark

07103

St. Joseph's Hosp. & Med. Ctr. of New Jersey, Paterson

009367344

San Juan City Hosp. PR NICHD CRS, San Juan

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

collaborator

MicroGeneSys Inc (nka Protein Sciences Corporation)

UNKNOWN

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH