A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT

PHASE2CompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

Not specified

Study Completion Date

June 30, 1995

Conditions
HIV Infections
Interventions
DRUG

Zalcitabine

Trial Locations (35)

10016

NYU Med. Ctr., Dept. of Medicine, New York

10029

Metropolitan Hosp. NICHD CRS, New York

10032

Columbia IMPAACT CRS, New York

10037

Harlem Hosp. Ctr. NY NICHD CRS, New York

10456

Bronx-Lebanon Hosp. IMPAACT CRS, The Bronx

11042

Schneider Children's Hosp., Div. of Infectious Diseases, New Hyde Park

11203

SUNY Downstate Med. Ctr., Children's Hosp. at Downstate NICHD CRS, Brooklyn

14642

Univ. of Rochester ACTG CRS, Rochester

19134

St. Christopher's Hosp. for Children, Philadelphia

20010

Children's National Med. Ctr., ACTU, Washington D.C.

21201

Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology, Baltimore

21287

Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases, Baltimore

27599

UNC at Chapel Hill School of Medicine - Dept. of Peds., Div. of Immunology & Infectious Diseases, Chapel Hill

27710

DUMC Ped. CRS, Durham

30303

Emory Univ. School of Medicine, Dept. of Peds., Div. of Infectious Diseases, Atlanta

33161

Univ. of Miami Ped. Perinatal HIV/AIDS CRS, Miami

60612

Cook County Hosp., Chicago

Univ. of Illinois College of Medicine at Chicago, Dept. of Peds., Chicago

60614

Chicago Children's CRS, Chicago

77030

Texas Children's Hosp. CRS, Houston

90095

UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CRS, Los Angeles

92093

UCSD Maternal, Child, and Adolescent HIV CRS, San Diego

94143

UCSF Pediatric AIDS CRS, San Francisco

94609

Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab., Oakland

Unknown

Tulane Med. Ctr. - Charity Hosp. of New Orleans, ACTU, New Orleans

Tulane/LSU Maternal/Child CRS, New Orleans

UMDNJ - Robert Wood Johnson, New Brunswick

North Shore-Long Island Jewish Health System, Dept. of Peds., Great Neck

San Juan City Hosp. PR NICHD CRS, San Juan

02115

HMS - Children's Hosp. Boston, Div. of Infectious Diseases, Boston

02118

BMC, Div. of Ped Infectious Diseases, Boston

01199

Baystate Health, Baystate Med. Ctr., Springfield

01655

WNE Maternal Pediatric Adolescent AIDS CRS, Worcester

00619

Univ. Hosp. Ramón Ruiz Arnau, Dept. of Peds., Bayamón

00936

Univ. of Puerto Rico Ped. HIV/AIDS Research Program CRS, San Juan

All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00000653 - A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT | Biotech Hunter | Biotech Hunter