A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

PHASE3CompletedINTERVENTIONAL
Enrollment

290

Participants

Timeline

Start Date

Not specified

Study Completion Date

September 30, 1994

Conditions
Pneumonia, Pneumocystis CariniiHIV Infections
Interventions
DRUG

Primaquine

DRUG

Sulfamethoxazole-Trimethoprim

DRUG

Dapsone

DRUG

Clindamycin

Trial Locations (32)

10003

Beth Israel Med. Ctr. (Mt. Sinai), New York

10016

NY Univ. HIV/AIDS CRS, New York

10021

Cornell University A2201, New York

14215

SUNY - Buffalo, Erie County Medical Ctr., Buffalo

14642

Univ. of Rochester ACTG CRS, Rochester

15213

Pitt CRS, Pittsburgh

27599

Unc Aids Crs, Chapel Hill

28203

Carolinas HealthCare System, Carolinas Med. Ctr., Charlotte

43210

The Ohio State Univ. AIDS CRS, Columbus

44106

Case CRS, Cleveland

46202

Indiana Univ. School of Medicine, Infectious Disease Research Clinic, Indianapolis

Methodist Hosp. of Indiana, Indianapolis

55455

University of Minnesota, ACTU, Minneapolis

60612

Rush Univ. Med. Ctr. ACTG CRS, Chicago

70112

Tulane Med. Ctr. - Charity Hosp. of New Orleans, ACTU, New Orleans

90033

USC CRS, Los Angeles

90502

Harbor-UCLA Med. Ctr. CRS, Torrance

96816

Univ. of Hawaii at Manoa, Leahi Hosp., Honolulu

Unknown

Stanford CRS, Palo Alto

Ucsf Aids Crs, San Francisco

Santa Clara Valley Med. Ctr., San Jose

San Mateo County AIDS Program, San Mateo

University of Colorado Hospital CRS, Aurora

Northwestern University CRS, Chicago

Johns Hopkins Adult AIDS CRS, Baltimore

Washington U CRS, St Louis

NYU Med. Ctr., Dept. of Medicine, New York

Regional Center for Infectious Disease, Wendover Medical Center CRS, Greensboro

Univ. of Cincinnati CRS, Cincinnati

University of Washington AIDS CRS, Seattle

02114

Massachusetts General Hospital ACTG CRS, Boston

02215

Beth Israel Deaconess - East Campus A0102 CRS, Boston

Sponsors
All Listed Sponsors
collaborator

Jacobus Pharmaceutical

INDUSTRY

collaborator

Glaxo Wellcome

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00000640 - A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS | Biotech Hunter | Biotech Hunter