A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children

PHASE3CompletedINTERVENTIONAL
Enrollment

819

Participants

Timeline

Start Date

Not specified

Study Completion Date

September 30, 1996

Conditions
HIV Infections
Interventions
DRUG

Zidovudine

DRUG

Didanosine

Trial Locations (80)

10003

Beth Israel Med Ctr / Pediatrics, New York

10016

Bellevue Hosp / New York Univ Med Ctr, New York

10021

Cornell Univ Med College, New York

10025

Saint Luke's - Roosevelt Hosp Ctr, New York

10029

Metropolitan Hosp Ctr, New York

Mount Sinai Med Ctr / Pediatrics, New York

10032

Columbia Presbyterian Med Ctr, New York

Incarnation Children's Ctr / Columbia Presbyterian Med Ctr, New York

10037

Harlem Hosp Ctr, New York

10451

Lincoln Hosp Ctr, The Bronx

10457

Bronx Lebanon Hosp Ctr / Pediatrics, The Bronx

Bronx Lebanon Hosp Ctr, The Bronx

10461

Albert Einstein College of Medicine, The Bronx

10595

Westchester Hosp, Valhalla

11021

North Shore Univ Hosp, Great Neck

11040

Schneider Children's Hosp, New Hyde Park

11203

King's County Hosp Ctr / Pediatrics, Brooklyn

SUNY - Brooklyn, Brooklyn

SUNY / Health Sciences Ctr at Brooklyn / Pediatrics, Brooklyn

12208

Children's Hosp at Albany Med Ctr, Albany

13210

SUNY Health Sciences Ctr at Syracuse / Pediatrics, Syracuse

14222

Children's Hosp Pact Prog / Children's Hosp of Buffalo, Buffalo

14642

Univ of Rochester Medical Center, Rochester

15219

Hemophilia Ctr of Western PA / Univ of Pittsburgh, Pittsburgh

20060

Howard Univ Hosp, Washington D.C.

21201

Univ of Maryland at Baltimore / Univ Med Ctr, Baltimore

29425

Med Univ of South Carolina, Charleston

30306

Emory Univ Hosp / Pediatrics, Atlanta

33161

Univ of Miami (Pediatric), Miami

35294

Univ of Alabama at Birmingham Schl of Med / Pediatrics, Birmingham

44106

Case Western Reserve Univ, Cleveland

48201

Children's Hosp of Michigan, Detroit

60612

Cook County Hosp, Chicago

Univ of Illinois College of Medicine / Pediatrics, Chicago

63104

St Louis Univ School of Medicine, St Louis

75235

Children's Med Ctr of Dallas, Dallas

77030

Hermann Hosp / Univ Texas Health Science Ctr, Houston

Texas Children's Hosp / Baylor Univ, Houston

90033

Los Angeles County - USC Med Ctr, Los Angeles

90801

Long Beach Memorial (Pediatric), Long Beach

91105

Huntington Memorial Hosp / Children's Hosp of Los Angeles, Pasadena

98105

Children's Hosp of Seattle, Seattle

117948111

State Univ of New York at Stony Brook, Stony Brook

191044318

Children's Hosp of Philadelphia, Philadelphia

191341095

Saint Christopher's Hosp for Children, Philadelphia

200072197

Georgetown Univ Med Ctr, Washington D.C.

200102916

Children's Hosp of Washington DC, Washington D.C.

212874933

Johns Hopkins Hosp - Pediatric, Baltimore

275997215

Univ of North Carolina, Chapel Hill

277103499

Duke Univ Med Ctr, Durham

381052794

Saint Jude Children's Research Hosp of Memphis, Memphis

432052696

Columbus Children's Hosp, Columbus

452292899

Cincinnati Children's Hosp / Univ Hosp, Cincinnati

606143394

Chicago Children's Memorial Hosp, Chicago

606371470

Univ of Chicago Children's Hosp, Chicago

802181088

Children's Hosp of Denver, Denver

900481804

Cedars Sinai / UCLA Med Ctr, Los Angeles

900951752

UCLA Med Ctr / Pediatric, Los Angeles

902422814

Kaiser Permanente / UCLA Med Ctr, Downey

905022004

Harbor - UCLA Med Ctr / UCLA School of Medicine, Los Angeles

920930672

UCSD Med Ctr / Pediatrics / Clinical Sciences, La Jolla

921036325

Univ of California / San Diego Treatment Ctr, San Diego

941430105

UCSF / Moffitt Hosp - Pediatric, San Francisco

943054149

Stanford Univ School of Medicine / Pediatrics, Stanford

946091809

Children's Hosp of Oakland, Oakland

06032

Univ of Connecticut Health Ctr, Farmington

06504

Yale Univ Med School, New Haven

021155724

Children's Hosp of Boston, Boston

02118

Boston City Hosp / Pediatrics, Boston

01199

Baystate Med Ctr of Springfield, Springfield

01655

Univ of Massachusetts Med Ctr, Worcester

089030019

UMDNJ - Robert Wood Johnson Med School / Pediatrics, New Brunswick

08903

Robert Wood Johnson Med School / Hershey Med Ctr, New Brunswick

07103

Saint Joseph's Hosp and Med Ctr/UMDNJ - New Jersey Med Schl, Newark

071072198

Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl, Newark

02903

Rhode Island Hosp / Brown Univ, Providence

00956

Ramon Ruiz Arnau Univ Hosp / Pediatrics, Bayamón

009365067

Univ of Puerto Rico / Univ Children's Hosp AIDS, San Juan

UPR Children's Hosp / UPR School of Medicine, San Juan

009367344

San Juan City Hosp, San Juan

Sponsors
All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

collaborator

Glaxo Wellcome

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00000637 - A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children | Biotech Hunter | Biotech Hunter