Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)

PHASE3CompletedINTERVENTIONAL
Enrollment

279

Participants

Timeline

Start Date

December 31, 1992

Primary Completion Date

March 31, 1995

Study Completion Date

March 31, 1995

Conditions
HIV InfectionsAcquired Immunodeficiency SyndromeCytomegalovirus Retinitis
Interventions
DRUG

Ganciclovir

intravenous ganciclovir induction at 5 mg/kg twice daily for 2 weeks followed by maintenance at 10 mg/kg/day

DRUG

Foscarnet

intravenous foscarnet induction at 90 mg/kg twice daily for 2 weeks, followed by maintenance therapy at 120 mg/kg/day

All Listed Sponsors
collaborator

National Eye Institute (NEI)

NIH

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

collaborator

Johns Hopkins University

OTHER

collaborator

University of Wisconsin, Madison

OTHER

collaborator

Baylor College of Medicine

OTHER

collaborator

Tulane University School of Medicine

OTHER

collaborator

Icahn School of Medicine at Mount Sinai

OTHER

collaborator

New York Presbyterian Hospital

OTHER

collaborator

New York University

OTHER

collaborator

Northwestern University

OTHER

collaborator

University of California, Los Angeles

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

University of California, San Diego

OTHER

collaborator

University of Miami

OTHER

collaborator

University of North Carolina, Chapel Hill

OTHER

collaborator

Memorial Sloan Kettering Cancer Center

OTHER

lead

Johns Hopkins Bloomberg School of Public Health

OTHER

NCT00000134 - Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) | Biotech Hunter | Biotech Hunter