About
Small Molecules for CNS Disorders
Areas of Focus
Categories
Small Molecule PharmaceuticalBoston & New England
Clinical Trials (15)
View allTotal Trials
15
As Lead Sponsor
7
As Collaborator
8
Total Enrollment
5,818
By Phase
PHASE2: 4PHASE1: 1PHASE4: 2PHASE3: 2PHASE2/PHASE3: 1EARLY_PHASE1: 2
By Status
COMPLETED: 7TERMINATED: 3RECRUITING: 2NOT_YET_RECRUITING: 1ACTIVE_NOT_RECRUITING: 1WITHDRAWN: 1
Clinical Trials Pipeline15 trials
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Phase 1/2
Phase 2/3
N/A
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Today
Hover over trial bars to see details
Recent Trials
NCT06580444Collaborator
Brexanolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study
PHASE2Not yet recruiting
40 participants
Started: Jul 28, 2025 · Completed: Mar 19, 2027
NCT05223829Collaborator
Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder
PHASE1Active, not recruiting
25 participants
Started: Aug 1, 2023 · Completed: Dec 31, 2025
NCT05254405Collaborator
An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
PHASE4Recruiting
20 participants
Started: Jun 1, 2023 · Completed: Mar 1, 2026
NCT05655520Lead Sponsor
A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease
PHASE3Terminated
153 participants
Started: Dec 14, 2022 · Completed: Jan 10, 2025
NCT05543746Collaborator
Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum Depression
N/ACompleted
10 participants
Started: Aug 5, 2022 · Completed: Nov 15, 2023
Locations (1)
Headquarters
Cambridge, MA, United States
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