Vascular / Surgical Devices
Total Trials
39
As Lead Sponsor
32
As Collaborator
7
Total Enrollment
10,701
NCT00334061
Study to Assess the Safety and Effectiveness of the Penumbra System
Phase: Phase 2
Role: Lead Sponsor
Start: Jun 30, 2006
Completion: Nov 30, 2007
NCT00785161
Penumbra Imaging Collaborative Study (PICS)
Phase: N/A
Start: Oct 31, 2008
Completion: Dec 31, 2010
NCT00963989
Imaging Guided Patient Selection for Interventional Revascularization Therapy
Start: Sep 30, 2009
Completion: Sep 30, 2016
NCT01193569
A Study of Survival and Outcome After Stroke
Start: Sep 30, 2010
Completion: Dec 22, 2016
NCT01465841
Study of the Penumbra Coil 400 System to Treat Aneurysm
Start: Nov 30, 2011
Completion: Jun 30, 2017
NCT01584609
A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke
Start: Apr 30, 2012
Completion: Dec 31, 2017
NCT01429350
Assess the Penumbra System in the Treatment of Acute Stroke
Phase: Phase 4
Start: May 31, 2012
Completion: Oct 31, 2016
NCT01636453
The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms
Start: Sep 30, 2012
Completion: Dec 31, 2016
NCT01092819
A Clinical Trial to Assess the Acute Safety and Functional Outcome and Recovery After STROKE: The FIRST Trial
Start: Dec 31, 2012
Completion: Dec 31, 2013
NCT01753388
Safety and Performance of the Penumbra Liberty Stent in the Treatment of Wide-Neck, Saccular, Intracranial Aneurysms
NCT01754051
A Volumetric Coiling in Aneurysm Registry of the Penumbra Coil 400TM System
Start: Jan 31, 2013
Completion: Oct 3, 2017
NCT02085551
Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery
Start: Mar 31, 2014
Completion: Sep 30, 2015
NCT02122133
CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400
Start: May 31, 2015
Completion: Oct 19, 2016
NCT02678169
European Registry on the ACE Reperfusion Catheters and the Penumbra System in the Treatment of Acute Ischemic Stroke
Start: Feb 29, 2016
Completion: Nov 30, 2017
NCT02729740
Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil
Start: Jun 3, 2016
Completion: Dec 27, 2019
NCT02216643
EndoVascular Treatment With Stent-retriever and/or Thromboaspiration vs. Best Medical Therapy in Acute Ischemic Stroke
Phase: Phase 3
Role: Collaborator
Start: Feb 8, 2017
Completion: Jun 30, 2019
NCT02079818
Visceral Artery Aneurysm Embolization by the Penumbra Ruby™ Coil System
Start: Jun 30, 2017
Completion: Sep 30, 2018
NCT03218566
Evaluating the Safety and Efficacy of the Indigo® Aspiration System in Acute Pulmonary Embolism
Start: Nov 22, 2017
Completion: Apr 5, 2019
NCT03342664
MIND: Artemis in the Removal of Intracerebral Hemorrhage
Start: Feb 6, 2018
Completion: Sep 23, 2024
NCT03464565
COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device
Start: Jul 2, 2018
Completion: Jan 17, 2020
NCT03608423
Dutch Intracerebral Hemorrhage Surgery Trial Pilot Study
Start: Dec 3, 2018
Completion: Apr 7, 2022
NCT03957473
Study of the CAT RX Aspiration Catheter When Used in Patients With Large Occlusive Thrombus in Coronary Arteries
Start: Aug 22, 2019
Completion: Jun 2, 2021
NCT04178746
PRONTO: Artemis in the Removal of Intraventricular Hemorrhage in the Hyper-Acute Phase
Start: Sep 26, 2019
NCT04106583
Assessing the WAVE Extra Soft Coil in Intracranial Aneurysms and Comparing Imaging Modalities
Start: Nov 5, 2019
Completion: Aug 2, 2023
NCT04144959
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo Aspiration System
Start: Dec 17, 2019
Completion: Oct 20, 2023
NCT04157270
LOTUS: Global Acute Stroke Study Utilizing Penumbra System
Start: Jan 12, 2020
Completion: May 10, 2021
NCT04297787
Safety and Efficacy of Thrombolysis in Combination With Endhole Aspiration in the Treatment of Acute DVT
Start: Sep 23, 2020
Completion: Jun 16, 2023
NCT04693767
Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
Start: Feb 16, 2021
Completion: Aug 3, 2022
NCT04798261
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
Start: Jun 25, 2021
Completion: Feb 29, 2028
NCT05003843
BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
Start: Sep 30, 2021
Completion: Feb 28, 2027
NCT05029414
EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke
Start: Dec 9, 2021
Completion: Jun 1, 2025
NCT05128955
Embolization of the Splenic Artery After Trauma
Start: May 10, 2022
Completion: Dec 31, 2026
NCT05437055
THUNDER: Acute Ischemic Stroke Study with the Penumbra System® Including Thunderbolt™ Aspiration Tubing
Start: Aug 11, 2022
Completion: Dec 10, 2024
NCT05460793
Dutch Intracerebral Hemorrhage Surgery Trial
Start: Nov 3, 2022
Completion: Jul 31, 2028
NCT05684796
Comparison of Two Pulmonary Embolism Treatments
Start: Nov 27, 2023
Completion: Oct 31, 2026
NCT06446024
Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan
Start: Dec 7, 2023
Completion: Aug 31, 2025
NCT06747117
A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)
Start: May 18, 2025
Completion: Jan 31, 2029
NCT06168058
Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices
Start: Aug 7, 2025
Completion: Jun 30, 2026
NCT07107022
Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).
Start: Nov 1, 2025
Completion: Dec 31, 2027
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