Sustained ophthalmic therapies with proprietary tailored hydrogels
Total Trials
56
As Lead Sponsor
31
As Collaborator
25
Total Enrollment
6,454
NCT00774228
I-ZIP Ocular Bandage Pivotal Study
Phase: N/A
Role: Lead Sponsor
Start: Oct 31, 2008
Completion: Aug 31, 2009
NCT01498224
ReSure Sealant Pivotal Study
Phase: Phase 3
Start: Dec 31, 2011
Completion: Nov 30, 2012
NCT01666210
Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
Phase: Phase 2
Start: Oct 31, 2012
Completion: Aug 31, 2013
NCT01800175
Non-Significant Risk Feasibility Study to Assess Retention and Replacement of the OTX Punctum Plug
Phase: Phase 1
Start: Feb 28, 2013
Completion: Not specified
NCT01845038
Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma
Start: Apr 30, 2013
Completion: May 31, 2014
NCT02034019
Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
Start: Feb 28, 2014
Completion: Feb 28, 2015
NCT02062905
OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
Start: Mar 31, 2014
Completion: Nov 30, 2014
NCT02089113
OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
Start: Apr 30, 2014
Completion: Mar 31, 2015
NCT02312544
Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension
Start: Nov 30, 2014
Completion: Dec 31, 2015
NCT02310815
ReSure Sealant Post Approval Study
Start: Dec 31, 2014
Completion: Apr 30, 2016
NCT02468700
OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye
Start: Jan 31, 2015
Completion: Nov 30, 2015
NCT02445326
OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
Start: Apr 30, 2015
Completion: Sep 30, 2015
NCT02988882
OTX-15-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
Start: Jun 30, 2015
Completion: Apr 27, 2016
NCT02736175
OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
Start: Oct 31, 2015
Completion: Jul 31, 2016
NCT02914509
Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT
Start: Nov 7, 2016
Completion: Mar 30, 2019
NCT04360174
CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension
Start: Apr 25, 2018
Completion: May 24, 2021
NCT04061044
A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert
Start: Jul 10, 2018
Completion: Sep 22, 2020
NCT03630315
CLN-0046: Treatment of AMD Subjects With OTX-TKI
Start: Feb 18, 2019
Completion: Jan 10, 2024
NCT04050865
A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis
Start: Aug 5, 2019
Completion: Feb 28, 2020
NCT04205916
A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery
Phase: Phase 4
Role: Collaborator
Start: Nov 4, 2019
Completion: Dec 1, 2020
NCT04316936
Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Acetate 1% Following Cataract Surgery
Start: Dec 10, 2019
Completion: Dec 23, 2020
NCT04462523
DEXTENZA for the Treatment of Postoperative Pain and Inflammation Following Vitreo-retinal Surgery
Start: Jan 3, 2020
Completion: Mar 31, 2022
NCT04200651
Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery
Start: Jan 13, 2020
Completion: Jul 12, 2023
NCT04168112
Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
Start: Feb 12, 2020
Completion: Apr 5, 2023
NCT04362670
Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease.
Phase: Phase 1/2
Start: Apr 23, 2020
Completion: Aug 11, 2021
NCT04371445
Dextenza in the Post-op Management of Vitreoretinal Surgeries
Start: Jun 1, 2020
Completion: Dec 1, 2025
NCT04396990
The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study
Start: Jun 8, 2020
Completion: Sep 28, 2020
NCT04426734
Evaluation of DEXTENZA in the Management of Pain and Inflammation in Patients With Anterior Uveitis Compared to Standard of Care Topical Corticosteroids
Start: Jul 1, 2020
Completion: Mar 31, 2021
NCT04464629
Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment
Start: Jul 14, 2020
Completion: Jan 25, 2023
NCT04413253
Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease
Start: Aug 1, 2020
Completion: Apr 11, 2022
NCT04413279
Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease
Completion: Jul 1, 2021
NCT04539548
A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
Start: Sep 4, 2020
Completion: Dec 21, 2023
NCT04527887
Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED)
Completion: Dec 31, 2024
NCT04403516
Dextenza in Pterygium Surgery
Start: Oct 1, 2020
Completion: Aug 5, 2021
NCT04563559
PREFERENTIAL Study
Phase: Phase 2/3
Start: Nov 30, 2020
Completion: Nov 30, 2021
NCT04687800
Clinical Investigation of the Dextenza 0.4mg Intracanalicular Insert Delivery System Used in Cataract Surgery
Start: Dec 1, 2020
Completion: Oct 24, 2022
NCT04563299
Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections
Start: Dec 9, 2020
Completion: Feb 14, 2023
NCT04530864
Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy
Start: Jan 31, 2021
Completion: Jul 31, 2021
NCT04747977
To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease
Start: Feb 12, 2021
Completion: Sep 22, 2021
NCT04529512
INtravitreal and Aqueous Dexamethasone Levels After DEXtenza
Start: Mar 31, 2021
NCT04863742
Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL
Start: Apr 26, 2021
Completion: Sep 30, 2021
NCT04708821
DEXTENZA Therapy for Treatment of Allergic Conjunctivitis
Start: Apr 30, 2021
Completion: Sep 2, 2021
NCT04945824
A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in Healthy Subjects
Phase: Early Phase 1
Start: Jun 1, 2021
Completion: Nov 1, 2022
NCT04989699
Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration
Start: Jul 28, 2021
Completion: Dec 18, 2023
NCT05023304
In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery
Start: Aug 23, 2021
Completion: Oct 1, 2022
NCT04728646
Evaluation of Dextenza in Patients With Ocular GVHD and Effects on Ocular Surface Disease Outcomes
Start: Sep 30, 2021
Completion: Dec 13, 2021
NCT05116345
DEXTENZA for the Treatment of Pain and Inflammation Following Surgical Trabeculectomy and Ahmed Valve Procedures
Start: Nov 30, 2021
Completion: Nov 30, 2023
NCT05143281
The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
Start: Dec 13, 2021
Completion: Feb 1, 2023
NCT05335122
A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)
Start: Mar 16, 2022
Completion: Jan 24, 2025
NCT05307081
An Observational, Qualitative Study Assessing Eye Drop Administration
Start: Apr 21, 2022
Completion: Dec 31, 2023
NCT05372315
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
Start: Jun 15, 2022
Completion: Oct 31, 2022
NCT05695417
Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy
Start: Jan 15, 2023
NCT05814757
OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)
Start: May 11, 2023
Completion: May 22, 2024
NCT06223958
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration
Start: Jan 29, 2024
Completion: Sep 27, 2027
NCT06495918
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration
Start: Nov 27, 2024
Completion: Jan 8, 2027
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