Small Molecules for Lipid-related Diseases
Total Trials
37
As Lead Sponsor
21
As Collaborator
16
Total Enrollment
11,624
NCT00003752
Bexarotene in Treating Patients With Metastatic Breast Cancer
Phase: Phase 2
Role: Lead Sponsor
Start: Oct 31, 1998
Completion: Mar 31, 2003
NCT00006345
Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma
Start: Nov 30, 1999
Completion: Mar 31, 2004
NCT00322296
Phase II Trial to Evaluate the Efficacy of Topical Bexarotene Gel in Patients With Parapsoriasis
Role: Collaborator
Start: Apr 30, 2001
Completion: Aug 31, 2004
NCT00211198
Study of ONTAK® to Treat Cutaneous T-Cell Lymphoma (CTCL)
Phase: Phase 4
Start: May 31, 2001
Completion: Jan 31, 2006
NCT00153842
A Study of Paclitaxel and Carboplatin in Combination With Bexarotene Oral Capsules in Patients With Advanced Lung Cancer
Phase: Phase 1/2
Start: Aug 31, 2001
Completion: Mar 31, 2009
NCT00141323
Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)
Phase: Phase 3
Start: Nov 30, 2001
Completion: Dec 31, 2007
NCT00306969
Study of Oral Bexarotene in Combination With Photopheresis for Treatment of Cutaneous T-Cell Lymphoma
Start: Dec 31, 2001
Completion: Apr 30, 2004
NCT01116622
Erlotinib (Tarceva) and Bexarotene (Targretin) Oral Capsules in Advanced Cancers of the Aerodigestive Tract
Phase: Phase 1
Start: Apr 30, 2003
Completion: Apr 30, 2014
NCT00163137
Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss
Start: May 31, 2003
Completion: Oct 31, 2005
NCT00063076
Phase II Randomized Bilateral Comparison of Topical Targretin Gel 1% in Alopecia Areata
Phase: Phase 2/3
Completion: May 31, 2007
NCT00073736
Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma
Start: Sep 30, 2003
Completion: Not specified
NCT00151008
Bexarotene With Narrow-Band UVB for Psoriasis
Start: Nov 30, 2003
Completion: Aug 31, 2005
NCT00238628
A Phase I/II Study of Bexarotene in Combination With ZD1839 (IRESSA®) in the Treatment of Non-Small Cell Lung Cancer
Start: Apr 30, 2004
Completion: Dec 31, 2005
NCT00143273
Dose Response Study of Lasofoxifene in Postmenopausal Women With Osteoporosis - Japanese Asian Dose Evaluation
Start: Jun 30, 2004
Completion: Mar 31, 2006
NCT00674453
The Prevention Of Postmenopausal Osteoporosis With Lasofoxifene And Cytokine Evaluation
Start: Sep 30, 2004
Completion: Sep 30, 2007
NCT00125359
Study of Tarceva and Targretin Oral Capsules in Patients With Advanced Lung Cancer
Start: Aug 31, 2005
Completion: Mar 31, 2014
NCT00125372
Study of Tarceva and Targretin in Stage I-II Lung Cancer
Phase: N/A
Start: Dec 31, 2005
Completion: Aug 31, 2010
NCT00938613
Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR
Start: Feb 28, 2007
Completion: Apr 30, 2007
NCT00458016
Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus
Start: Mar 31, 2007
Completion: Mar 31, 2008
NCT00522925
A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension
Start: Aug 31, 2007
Completion: May 31, 2008
NCT00623324
The Effects of Aplindore on the Treatment of Signs and Symptoms of Parkinson's Disease
Start: Jan 31, 2008
NCT00626418
The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome
Start: Feb 29, 2008
NCT00940953
Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis
NCT00635232
A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension
Start: Mar 31, 2008
Completion: Dec 31, 2008
NCT00879112
Study of MB07811 in Subjects With Hypercholesterolemia
Start: Apr 30, 2009
Completion: Dec 31, 2009
NCT01128959
Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy
Start: Jun 30, 2010
Completion: Jan 31, 2013
NCT01919684
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus
Start: Nov 30, 2013
NCT02250222
Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus
Start: Oct 31, 2014
Completion: Jun 30, 2015
NCT02672839
A Comparison Study of the Bioavailability of a Capsule Formulation of LGD-6972 to an Oral Solution Formulation
Start: Feb 29, 2016
Completion: May 31, 2016
NCT02851849
A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus
Start: Sep 30, 2016
Completion: Jun 30, 2017
NCT03869983
Relative Bioavailability of CE-Iohexol (Captisol-enabled™ Iohexol) Injection and Omnipaque™ Injection
Start: Apr 12, 2019
Completion: Jun 15, 2019
NCT04309526
Safety, Tolerability and Pharmacokinetics of NCO-48 Fumarate in Healthy Subjects
Start: Mar 18, 2020
Completion: Oct 13, 2020
NCT04629976
Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B
Start: Jan 12, 2021
Completion: Dec 28, 2022
NCT04627831
Comparison of Captisol-Enabled™ Iohexol and Omnipaque™ in Patients With Impaired Renal Function Undergoing Coronary Angiography
Start: Jan 31, 2022
Completion: Apr 30, 2023
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