Monoclonal Antibodies
Total Trials
10
As Lead Sponsor
9
As Collaborator
1
Total Enrollment
346
NCT00630643
NI-0401 in Active Crohn's Disease
Phase: Phase 1/2
Role: Lead Sponsor
Start: Jan 31, 2006
Completion: Dec 31, 2007
NCT00805909
NI-0401 in Patients With Acute Renal Allograft Rejection
Start: Aug 31, 2007
Completion: Jan 31, 2009
NCT01808469
First in Human Study of an Anti-Toll-like Receptor 4 (TLR4) Monoclonal Antibody (NI-0101) in Adult Healthy Volunteers
Phase: Phase 1
Start: Nov 30, 2012
Completion: Mar 31, 2014
NCT03241108
Study of an Anti-TLR4 mAb in Rheumatoid Arthritis
Phase: Phase 2
Start: May 10, 2017
Completion: Jun 20, 2018
NCT03985423
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH
Phase: Phase 2/3
Role: Collaborator
Start: Jun 2, 2020
Completion: Jun 29, 2021
NCT05403554
A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers
Start: Apr 29, 2022
Completion: Sep 30, 2026
NCT06663839
A Study of NILK-2301 in Patients with Locally Advanced or Metastatic Low Tumor Volume (LTV) Colorectal Cancer
Start: Apr 12, 2024
Completion: Jan 31, 2026
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