Small Molecules
Total Trials
16
As Lead Sponsor
As Collaborator
0
Total Enrollment
3,789
NCT01952535
A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral HMS5552 in Healthy Volunteers
Phase: Phase 1
Role: Lead Sponsor
Start: Sep 30, 2013
Completion: Dec 31, 2013
NCT02077452
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 Diabetes
Start: Mar 31, 2014
Completion: Oct 31, 2014
NCT02386982
Beta Cell Function and Related Pharmacodynamics of HMS5552 in T2DM Patients
Start: Mar 31, 2015
Completion: May 31, 2015
NCT02561338
A Multi-center 12-week Study of HMS5552 in T2DM
Phase: Phase 2
Start: Sep 30, 2015
Completion: Sep 30, 2016
NCT02597400
Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM
Start: Oct 31, 2015
Completion: Oct 31, 2015
NCT03158506
Human Mass Balance Study of HMS5552 in Healthy Subjects
Start: Mar 29, 2017
Completion: Apr 6, 2017
NCT03173391
Long-term Efficacy and Safety of HMS5552 in T2DM Subjects
Phase: Phase 3
Start: Jul 18, 2017
Completion: Nov 30, 2020
NCT04080596
DDI Study to Investigate the Impact of Itraconazole on the Pharmacokinetics of Dorzagliatin
Start: Oct 13, 2017
Completion: Dec 5, 2017
NCT03141073
Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects
Start: Oct 15, 2017
Completion: Feb 28, 2021
NCT04080609
DDI Study Between Dorzagliatin and Rifampicin
Start: Mar 27, 2018
Completion: Apr 17, 2018
NCT03790839
Drug Interaction Study Between Dorzagliatin and Sitagliptin
Start: Jan 31, 2019
Completion: Aug 30, 2019
NCT04426708
A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers
Start: Feb 18, 2019
Completion: Jul 3, 2020
NCT03790787
Drug Interaction Study Between Dorzagliatin and Empagliflozin
Start: Apr 18, 2019
Completion: Mar 15, 2020
NCT04324424
A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers
Start: Apr 23, 2019
Completion: Sep 30, 2019
NCT06263348
A Post-Marketing Safety Study of Dorzagliatin in Patients With Type 2 Diabetes
Phase: Phase 4
Start: Dec 20, 2023
Completion: Apr 30, 2026
NCT06498284
Evaluate HM-002-1005 in Subjects With Type 2 Diabetes Mellitus
Start: Apr 25, 2024
Completion: Sep 6, 2024
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