Small Molecules
Total Trials
64
As Lead Sponsor
49
As Collaborator
15
Total Enrollment
9,464
NCT00492037
Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia
Phase: Phase 3
Role: Lead Sponsor
Start: Jan 31, 2000
Completion: Feb 28, 2002
NCT00380575
Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia
Start: Aug 31, 2000
Completion: Feb 28, 2003
NCT01131000
Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Adult Febrile Patients
Start: Jun 30, 2002
Completion: Aug 31, 2005
NCT00057356
Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure
Phase: Phase 2
Start: Nov 30, 2002
Completion: Mar 31, 2004
NCT00061633
Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Start: Jun 30, 2003
Completion: Jan 31, 2004
NCT00062647
Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremia
Start: Aug 31, 2003
Completion: Aug 31, 2006
NCT00077675
Phase 2 Trial of TD-6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Start: Feb 29, 2004
Completion: Sep 30, 2004
NCT00379847
An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia
Completion: Jun 30, 2005
NCT00091819
Comparison of Telavancin and Vancomycin for Complicated Skin and Skin Structure Infections With a Focus on Methicillin-resistant Staphylococcus Aureus
Start: Jan 31, 2005
Completion: Jun 30, 2006
NCT00124020
Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus
Completion: May 31, 2007
NCT00225732
Trial of Caldolor for Treatment of Pain in Post-Operative Adult Patients
Completion: Jan 31, 2008
NCT00107952
Start: Feb 28, 2005
Completion: Jul 31, 2007
NCT00107978
Completion: May 31, 2006
NCT00225706
A Study of Caldolor in Hospitalized Febrile Pediatric Patients
Start: Oct 31, 2005
Completion: Aug 31, 2007
NCT00435591
A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
Phase: Phase 4
Start: Jan 31, 2007
Completion: Sep 30, 2008
NCT00939913
Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy
Role: Collaborator
Completion: May 31, 2010
NCT00478192
Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
Start: Apr 30, 2007
Completion: Aug 31, 2008
NCT00470600
Efficacy and Safety Study of Caldolor (IV Ibuprofen) in Hospitalized Adult Orthopedic Patients
Start: May 31, 2007
NCT00470743
Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies
Completion: Jun 30, 2009
NCT00780962
N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients
Start: Oct 16, 2007
Completion: Aug 9, 2010
NCT00606489
Efficacy and Safety Study of Caldolor (Intravenous Ibuprofen) in Hospitalized Adult and Pediatric Burn Patients
Start: Nov 30, 2007
Completion: May 31, 2009
NCT00592475
A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients
Start: Dec 31, 2007
Completion: Nov 30, 2008
NCT00851227
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function
Phase: Phase 1
Start: Feb 28, 2009
Completion: Jan 31, 2010
NCT00867880
Pharmacokinetic Study Of Ibuprofen Injection (IVIb) In Healthy Adult Subjects
Start: Mar 31, 2009
NCT00843986
Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)
Start: Apr 30, 2009
Completion: Aug 31, 2009
NCT00887627
Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function
Completion: Jul 31, 2010
NCT00889538
Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems
Phase: N/A
Completion: Sep 30, 2012
NCT00712543
A Preference Study Comparing Kristalose® and Liquid Lactulose
Start: Jun 30, 2009
Completion: Sep 30, 2009
NCT01130324
VIBATIV Pregnancy Registry
Start: Nov 30, 2009
Completion: Oct 31, 2020
NCT01002573
Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
Start: Jul 31, 2010
Completion: Jun 30, 2013
NCT01118663
Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection
Start: Sep 30, 2010
Completion: May 31, 2013
NCT01238796
A Study to Evaluate the Effect of Renal Function on the Biological Activity of Telavancin
Start: Dec 31, 2010
Completion: Feb 28, 2011
NCT01256541
Kristalose as Bowel Evacuant Prior to Colonoscopy
Completion: Sep 30, 2011
NCT01297829
Does Preoperative Caldolor Decrease the Requirement for Postoperative Narcotics
Start: Feb 28, 2011
Completion: Mar 31, 2015
NCT01370148
A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan
Start: Apr 30, 2011
Completion: Feb 28, 2014
NCT01334944
Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen
Start: Jun 30, 2011
Completion: Oct 31, 2012
NCT01334957
Surgical Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen
Completion: Jan 31, 2013
NCT01332253
Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy
Start: Jul 31, 2011
Completion: Aug 31, 2012
NCT01436500
Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients
Start: Oct 31, 2011
Completion: Jul 31, 2015
NCT01514175
A Pilot Study Comparing the Analgesic Efficacy of IV Ibuprofen and IV Ketorolac
Start: Jan 31, 2012
Completion: Dec 31, 2012
NCT01451411
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia
Start: Feb 29, 2012
Completion: Jan 31, 2014
NCT01650870
Safety, Efficacy, and Patient Preference of Split-Dose Crystalline Lactulose as a Preparation for Colonoscopy in Adults
Start: Jul 31, 2012
NCT01650519
A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery
Start: Sep 30, 2012
NCT01530880
Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage
Start: Oct 31, 2012
Completion: Mar 17, 2016
NCT01707251
Intravenous Ibuprofen for Laparoscopic Bariatric Surgery
NCT01773005
Caldolor Versus Caldolor Plus OFIRMEV in Total Knee or Hip Arthroplasty Surgeries
Start: Dec 31, 2012
Completion: Dec 31, 2014
NCT01887470
2 Regimens of Lactulose for Colonoscopy Preparation in Adults
Start: Jul 31, 2013
Completion: Oct 31, 2013
NCT01901393
Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery
Completion: Aug 31, 2014
NCT02123017
Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
Start: Apr 30, 2014
NCT02216357
Trial to Determine the Safety of Oral Ifetroban in Patients With a History of Aspirin Exacerbated Respiratory Disease
Start: Aug 31, 2014
Completion: Jan 31, 2016
NCT02288234
Telavancin Observational Use Registry (TOUR)
Start: Nov 30, 2014
Completion: Oct 31, 2017
NCT02013141
Telavancin Pediatric PK Study (Ages >12 Months to 17 Years)
Start: Dec 31, 2014
Completion: Mar 31, 2021
NCT02208063
A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial
Completion: Apr 12, 2018
NCT02682511
Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension
Start: Jan 31, 2017
Completion: May 31, 2026
NCT02802228
Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients
Start: Mar 6, 2017
Completion: Jul 17, 2018
NCT03028350
Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)
Start: Jul 17, 2017
Completion: Apr 25, 2023
NCT02583399
Safety and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
Start: Aug 8, 2017
Completion: Jul 2, 2019
NCT03172793
Telavancin Pharmacokinetics in Cystic Fibrosis Patients
Completion: Apr 17, 2019
NCT03611010
Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients
Start: Aug 7, 2018
Completion: Feb 24, 2020
NCT03694249
Ifetroban in Treating Patients With Malignant Solid Tumors at High Risk of Metastatic Recurrence
Start: Dec 12, 2018
Completion: Apr 30, 2026
NCT03962855
Thromboxane Receptor Antagonist to Improve Endothelial Function
Start: Sep 20, 2019
Completion: Nov 15, 2022
NCT03340675
Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy
Start: Oct 19, 2020
Completion: Dec 31, 2025
NCT05571059
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Start: Jan 31, 2024
Completion: Jan 31, 2026
NCT06119061
Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With Subarachnoid Hemorrhage
Start: Jul 2, 2024
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