Treatments for hormone-driven cancers
Total Trials
8
As Lead Sponsor
4
As Collaborator
Total Enrollment
213
NCT03909152
A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone
Phase: Phase 2
Role: Collaborator
Start: May 2, 2019
Completion: Sep 3, 2024
NCT04719273
Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial Cancer
Start: Jan 28, 2021
Completion: Dec 31, 2025
NCT04872608
A Study of Letrozole, Palbociclib, and Onapristone ER in People With Metastatic Breast Cancer
Phase: Phase 1
Start: Sep 9, 2021
Completion: Apr 25, 2023
NCT04738292
Onapristone and Fulvestrant for ER+ HER2- Metastatic Breast Cancer After Endocrine Therapy and CDK4/6 Inhibitors (The SMILE Study)
Start: Oct 5, 2021
Completion: May 15, 2023
NCT05618613
Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer
Phase: Phase 1/2
Role: Lead Sponsor
Start: Dec 2, 2022
Completion: Jun 23, 2023
NCT06938711
A Rollover Protocol of Elacestrant, in Combination With Onapristone, for Patients With ER+, PR+, HER2- Advanced or Metastatic Breast Cancer
Start: Jun 30, 2023
Completion: Dec 31, 2023
NCT06515613
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
Start: Jul 10, 2024
Completion: Mar 31, 2028
NCT06756035
CT-95 in Advanced Cancers Associated With Mesothelin Expression
Start: Mar 31, 2025
Completion: Dec 31, 2028
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