Gene Editing, Gene Expression, Bioprocessing
Total Trials
14
As Lead Sponsor
13
As Collaborator
1
Total Enrollment
2,672
NCT00647296
Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS)
Phase: Phase 2
Role: Lead Sponsor
Start: Apr 9, 2008
Completion: Sep 4, 2009
NCT00931944
Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)
Start: Jul 31, 2009
Completion: Jul 31, 2013
NCT01281189
Phase 3 Study of Dexpramipexole in ALS
Phase: Phase 3
Start: Mar 31, 2011
Completion: Nov 30, 2012
NCT01424176
Dexpramipexole Renal PK Study
Phase: Phase 1
Start: Jul 31, 2011
Completion: Jan 31, 2012
NCT01424163
Dexpramipexole Japanese PK Study
Start: Aug 31, 2011
Completion: Feb 29, 2012
NCT01449578
Dexpramipexole SAD/MAD Study
Start: Nov 30, 2011
NCT01511029
Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)
Start: Jan 31, 2012
Completion: May 31, 2012
NCT01536249
Dexpramipexole and Cimetidine Drug Drug Interaction (DDI)
Start: Mar 31, 2012
Completion: Apr 30, 2012
NCT01597310
Dexpramipexole and Warfarin Drug Drug Interaction (DDI) Study
Start: May 31, 2012
Completion: Jul 31, 2012
NCT01607034
Study in Healthy Volunteers of the Bioavailability of Dexpramipexole Tablets and Food Effects
Start: Jun 30, 2012
NCT01622088
Phase 3 Extension Study of Dexpramipexole in ALS
Completion: Feb 28, 2013
NCT02101138
Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome
Role: Collaborator
Start: Mar 14, 2014
Completion: Oct 23, 2019
NCT02217332
Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia
Start: Aug 31, 2014
Completion: Jan 20, 2017
NCT04046939
Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma
Start: Aug 15, 2019
Completion: Mar 2, 2021
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