Cellular Therapies
Total Trials
41
As Lead Sponsor
37
As Collaborator
4
Total Enrollment
2,245
NCT00591136
Phase I Study of Indibulin in Patients With Solid Tumors
Phase: Phase 1
Role: Lead Sponsor
Start: Apr 30, 2003
Completion: Sep 30, 2008
NCT00592046
A Phase I Trial of ZIO-101 in Hematologic Cancers
Start: May 31, 2005
Completion: Jun 30, 2008
NCT00509782
Phase I Trial of ZIO-101 in Patients With Solid Tumors
Role: Collaborator
Completion: Apr 30, 2008
NCT00591396
A Phase I Trial of ZIO-101 in Solid Tumors
Start: Jul 31, 2005
Completion: Jul 31, 2008
NCT00303199
Study of ZIO-101 in Multiple Myeloma
Phase: Phase 1/2
Start: Jan 31, 2006
Completion: Aug 31, 2007
NCT00421135
A Protocol for the Safety and Tolerance of Intravenous Isophosphoramide Mustard (IPM) in Patients With Advanced Cancer
Start: Feb 28, 2006
Completion: Oct 31, 2007
NCT00439686
Study of ZIO-201 in Advanced Sarcoma
Completion: Dec 31, 2013
NCT00421213
Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers
Phase: Phase 2
Start: Dec 31, 2006
Completion: Apr 30, 2012
NCT00423306
A Phase-II Trial of ZIO 101 in Advanced Hepatocellular Carcinoma
Start: Jan 31, 2007
NCT00423644
A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b
NCT00591292
Phase I Study in Advanced Solid Tumors
Start: Jun 30, 2007
Completion: Jun 30, 2013
NCT00591422
Phase I Study of Oral Darinaparsin (ZIO-101-C)in Advanced Solid Tumors and Non-Hodgkin's Lymphomas
Start: Aug 31, 2007
NCT00591890
Phase IB Study of Indibulin Using Positron-Emission Tomography (PET) Scans
Start: Oct 31, 2007
Completion: Mar 31, 2009
NCT00592163
Phase I Study of Oral ZIO-101-C in Advanced Solid Tumors and Lymphomas
Start: Dec 31, 2007
NCT00591383
Phase I Study of Indibulin in Combination With Erlotinib in Advanced Solid Tumors
Start: Jan 31, 2008
NCT00608803
Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors
Completion: Jan 31, 2009
NCT00607711
Study of Oral Palifosfamide Tris in Solid Tumors
Start: Mar 31, 2008
Completion: Nov 30, 2009
NCT00726687
Phase 1b Study of Indibulin in Combination With Capecitabine in Advanced Solid Tumors
Start: Jun 30, 2008
NCT00718484
A Study of Palifosfamide Tris Plus Doxorubicin Versus Doxorubicin in Unresectable or Metastatic Soft-tissue Sarcoma
Start: Aug 31, 2008
Completion: Apr 30, 2014
NCT00815607
Trial of an Intratumoral Injections of INXN-3001 in Subjects With Stage III or IV Melanoma
Start: Apr 30, 2009
Completion: Jan 31, 2013
NCT01113970
Study of a Novel Indibulin Dosing Schedule for the Treatment of Metastatic Breast Cancer
Start: Mar 31, 2010
Completion: May 31, 2013
NCT01139346
Study of Oral Darinaparsin in Patients With Advanced Solid Tumors
Start: Jun 30, 2010
NCT01139359
Safety Study of Darinaparsin in Combination With Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) to Treat Lymphoma
Completion: Jun 30, 2011
NCT01168791
Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue Sarcoma
Phase: Phase 3
Start: Jul 31, 2010
Completion: Mar 31, 2013
NCT01242072
Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies
Start: Nov 30, 2010
Completion: Dec 31, 2012
NCT00968760
CD19-specific T Cell Infusion in Patients With B-Lineage Lymphoid Malignancies
Start: Jun 20, 2011
Completion: Apr 23, 2020
NCT01340547
Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjects With Advanced Solid Tumors
Start: Jun 30, 2011
Completion: Sep 30, 2013
NCT01397708
Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma
Start: Aug 31, 2011
Completion: Sep 30, 2014
NCT01492036
Long-Term Follow-Up of Recipient of Gene Transfer Research
Phase: N/A
Start: Dec 9, 2011
Completion: Dec 31, 2027
NCT01555710
Study of Palifosfamide-tris in Combination With Carboplatin and Etoposide in Chemotherapy Naïve Patients With Extensive-Stage Small Cell Lung Cancer (The MATISSE Study)
Start: May 31, 2012
Completion: Jun 30, 2015
NCT01808534
Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors
Start: Feb 28, 2013
Completion: Nov 30, 2014
NCT01703754
Adenoviral Vector Monotherapy or Combination With Chemotherapy in Subjects With Recurrent/Metastatic Breast Cancer.
Start: Apr 4, 2013
Completion: Aug 7, 2014
NCT02026271
A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma
Start: Jun 30, 2015
Completion: Aug 31, 2019
NCT02423902
A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer
Start: Jul 18, 2015
Completion: Jul 19, 2016
NCT03330197
A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG
Start: Sep 26, 2017
Completion: Sep 10, 2021
NCT03636477
A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102
Start: Jun 18, 2018
Completion: Jun 30, 2021
NCT03679754
Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102
Start: Sep 5, 2018
Completion: Jan 19, 2021
NCT04006119
Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma
Start: Aug 1, 2019
Completion: Aug 5, 2021
NCT05124743
HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors
Start: Sep 24, 2021
Completion: Aug 14, 2023
NCT05194735
Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors
Start: Apr 4, 2022
Completion: Nov 30, 2024
NCT05292859
Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
Start: Mar 1, 2023
Completion: May 30, 2025
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