Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

PHASE4RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

October 7, 2025

Primary Completion Date

March 31, 2027

Study Completion Date

May 31, 2027

Conditions
ProteinuriaImmunoglobulin A (IgA) NephropathyFocal Segmental GlomerulosclerosisKidney Transplant
Interventions
DRUG

Sparsentan

"For participants with a kidney transplant with IgAN:~Day 1 through Week 2 visit, patients will take 200 mg once daily (QD) prior to the morning meal. At the Week 2 visit, patients will titrate up to 400 mg QD and take this dose through Week 36, if tolerated and determined to be safe by the Investigator.~For participants with a kidney transplant with FSGS:~Day 1 through Week 2 visit, patients will take 400 mg QD prior to the morning meal. At the Week 2 visit, patients will titrate up to 800 mg QD and take this dose through Week 36, if tolerated and determined to be safe by the Investigator."

Trial Locations (3)

43210

RECRUITING

Ohio State University, Columbus

53705

RECRUITING

University of Wisconsin, Madison

75204

RECRUITING

Dallas Nephrology Associates, Dallas

All Listed Sponsors
lead

Travere Therapeutics, Inc.

INDUSTRY