The AccelERate Trial

NARecruitingINTERVENTIONAL
Enrollment

288

Participants

Timeline

Start Date

October 2, 2025

Primary Completion Date

March 31, 2028

Study Completion Date

December 31, 2028

Conditions
Pelvic Organ ProlapsePelvic Organ Prolapse (POP)Pelvic Organ Prolapse Vaginal SurgeryPelvic Organ Prolapse, Patient Education
Interventions
BEHAVIORAL

Postoperative Exercise regimen

The intervention arm will be instructed to perform 30 minutes of medium intensity exercise (vigorous enough to cause shortness of breath, but light enough to be able to maintain a conversation) starting on postoperative day 3 and continuing at least 5 times weekly for 6 weeks. Participants in the intervention group will be allowed to select their preferred physical activity, and the activity will be performed without supervision. Participants in the control group will be given typical postoperative instructions with gradual resumption of activity.

Trial Locations (6)

19104

NOT_YET_RECRUITING

University of Pennsylvania, Philadelphia

27707

NOT_YET_RECRUITING

Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery, Durham

60637

RECRUITING

University of Chicago, Chicago

92110

NOT_YET_RECRUITING

Kaiser Permanente -- San Diego, San Diego

92121

NOT_YET_RECRUITING

University of California - San Diego, San Diego

02903

NOT_YET_RECRUITING

Brown/ Women and Infants Hospital of Rhode Island, Division of Urogynecology and Reconstructive Pelvic Surgery, Providence

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

RTI International

OTHER

collaborator

University of California, San Diego

OTHER

collaborator

University of Chicago

OTHER

collaborator

Duke University

OTHER

collaborator

Women and Infants Hospital of Rhode Island

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

Kaiser Permanente

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

NICHD Pelvic Floor Disorders Network

NETWORK