Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure

NANot yet recruitingINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

November 1, 2027

Study Completion Date

November 15, 2027

Conditions
Shoulder SurgeryObesity
Interventions
PROCEDURE

Ultrasound-Guided Interscalene Brachial Plexus Block

"Single 16 mL injection (15 mL 0.5 % bupivacaine + 1 mL dexamethasone 4 mg) at the C5-C6 root level under ultrasound guidance.~Performed pre-operatively as standard care for shoulder surgery. Arm Cross-Reference: Standard Interscalene Block (Control)"

PROCEDURE

Phrenic-Sparing Block Combination (Experimental)

"Infraclavicular: 15 mL (75 mg) 0.5 % bupivacaine + 1 mL dexamethasone (4 mg) injected around the cords of the brachial plexus beneath the clavicle under ultrasound guidance.~Distal Suprascapular: 12 mL (60 mg) 0.5 % bupivacaine + 1 mL (4 mg) dexamethasone injected at the suprascapular notch under ultrasound guidance to provide complete shoulder coverage while minimizing phrenic nerve involvement. Total local anesthetic dose = 135 mg bupivacaine + 8 mg dexamethasone.~Arm Cross-Reference: Phrenic-Sparing Block Combination (Experimental)"

DRUG

Bupivacaine HCl 0.5% Injectable Solution

"Infraclavicular: Adminstered as 15 mL (75 mg) injection (together with dexamethasone).~Distal Suprascapular: Adminstered as 12 mL (60 mg) injection (together with dexamethasone)."

DRUG

Dexamethasone 4mg

Adminstered as applicable for infraclavicular and distal suprascapular: as 1 mL (4 mg) injection (together with bupicacaine 0.5%).

Trial Locations (1)

27599

University of North Carolina Hospitals, Chapel Hill

All Listed Sponsors
collaborator

American Society of Regional Anesthesia

OTHER

lead

University of North Carolina, Chapel Hill

OTHER

NCT07216820 - Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure | Biotech Hunter | Biotech Hunter