Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Opioid UseSurgical RecoveryVaginal HysterectomyProlapse PelvicPostoperative Pain
Interventions
DRUG

Bupivacaine-epinephrine

Participants randomized to this experimental arm will receive a paracervical block with 10 mL 0.5% bupivacaine with epinephrine before their vaginal hysterectomy and prolapse repair

DRUG

Normal saline

Participants randomized to this experimental arm will receive a placebo paracervical injection with 10 mL 0.5% normal saline before their vaginal hysterectomy and prolapse repair

Trial Locations (1)

27607

University of North Carolina Urogynecology and Reconstructive Pelvic Surgery at REX, Raleigh

All Listed Sponsors
lead

University of North Carolina, Chapel Hill

OTHER