Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension

NARecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

August 31, 2027

Study Completion Date

February 29, 2028

Conditions
Hypertension (HTN)
Interventions
BEHAVIORAL

Isometric Exercise and Lifestyle Change Advice

"The intervention consists of two distinct phases:~• Intensive Phase (12 weeks) - a structured, high-support period involving three weekly supervised isometric exercise sessions and lifestyle change advice. The supervised exercise programme will consist of 4 × 2-minute bouts of wall squat exercise, with 2-minute rest periods between bouts. Participant squat height position will be based on individual calculations determined at baseline. Target rate of perceived exertion (RPE) for each bout will be:~* Bout 1: RPE 4 (target range: 3.5-4.5)~* Bout 2: RPE 5.5 (target range: 5-6)~* Bout 3: RPE 7 (target range: 6.5-7.5)~* Bout 4: RPE 8.5 (target range: 8-9) If the RPE falls outside the target zone for a given bout, participants will adjust their squat height accordingly.~Lifestyle change advice will be given in booklet form in accordance with current NICE guidelines for hypertension.~• Maintenance Phase (12-24 weeks) - focus on sustaining exercise and lifestyle behaviour changes"

BEHAVIORAL

Lifestyle Change Advice

Lifestyle change advice given as per current standard care for hypertension

Trial Locations (1)

NE1 8ST

RECRUITING

Northumbria University, Newcastle upon Tyne

All Listed Sponsors
collaborator

HealthWorks Newcastle Upon Tyne

UNKNOWN

lead

Northumbria University

OTHER

NCT07213479 - Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension | Biotech Hunter | Biotech Hunter