Effect of IMT in Patients After Acute Exacerbations of COPD

NANot yet recruitingINTERVENTIONAL
Enrollment

358

Participants

Timeline

Start Date

December 1, 2025

Primary Completion Date

June 30, 2028

Study Completion Date

February 28, 2029

Conditions
Chronic Obstructive Pulmonary DiseasesCOPDSymptom Exacerbation
Interventions
OTHER

Training

"home-based inspiratory muscle training (IMT) will be delivered using a portable IMT device connected via Bluetooth to a smartphone application that provides real-time feedback, adherence monitoring, and telemonitoring by the study team. Patients will train for 365 days following hospital discharge due to an acute exacerbation of COPD:~* Intensive phase (Day 0-90): 2 daily sessions, each consisting of 30 breaths against an inspiratory load set by thetelemonitor, with regular online supervised IMT sessions, 7 sessions in total~* Maintenance phase (Day 91-180): One daily session of 30 breaths, with sporadic online supervised IMT sessions, 2 sessions in total.~* Follow-up phase (Day 181-365): Participants may continue IMT unsupervised. Supervision includes both in-person sessions at hospital visits and online sessions with telemonitors."

Trial Locations (12)

1000

Centre Hospitalier Universitaire Saint-Pierre, Brussels

1070

Campus Joseph Bracops, Hôpitaux Iris Sud, Anderlecht

2650

Universitair Ziekenhuis Antwerpen, Edegem

3000

University Hospitals Leuven, Leuven

4000

Centre hospitalier universitaire de Liège, Liège

5530

Centre Hospitalier Universitaire UCL Namur, Yvoir

6000

Grand Hopial de Charleroi, Charleroi

8500

AZ Groeninge, Kortrijk

8800

AZ Delta, Roeselare

9000

AZ Maria Middelares, Ghent

Universitair Ziekenhuis Gent, Ghent

9300

AZORG, Aalst

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Hopitaux Iris Sud

UNKNOWN

collaborator

Centre Hospitalier Universitaire Saint Pierre

OTHER

collaborator

Onze Lieve Vrouw Hospital

OTHER

collaborator

AZ Delta

OTHER

collaborator

University Hospital, Antwerp

OTHER

collaborator

Algemeen Ziekenhuis Maria Middelares

OTHER

collaborator

Grand Hôpital de Charleroi

OTHER

collaborator

Centre Hospitalier Universitaire UCLouvain Namur

OTHER

collaborator

Centre Hospitalier Universitaire de Liege

OTHER

collaborator

General Hospital Groeninge

OTHER

collaborator

University Hospital, Ghent

OTHER

lead

KU Leuven

OTHER

NCT07213128 - Effect of IMT in Patients After Acute Exacerbations of COPD | Biotech Hunter | Biotech Hunter