The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)

NARecruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 15, 2025

Primary Completion Date

May 15, 2027

Study Completion Date

June 15, 2027

Conditions
Gastrointestinal MalignancyPain Control
Interventions
PROCEDURE

Erector Spinae Plane Block

The abdominal viscera, from the stomach to midway through the sigmoid colon, derives its sensory innervation from afferent fibers that travel with, but are distinct from, the sympathetic nerve fibers from the 5th thoracic (T5) to the 2nd lumbar (L2) spinal levels (Moore et al). These fibers converge at the celiac plexus, located near the celiac artery and the aorta. From there, they bifurcate into the paravertebral sympathetic chain and subsequently ascend to the spinal cord and integrate into the central nervous system (Lohse et al). The celiac plexus block is an invasive procedure performed by an interventional anesthesiologist or palliative care specialist to lyse the celiac plexus and has been shown to reduce pain and opiate use in patients suffering from GI malignancy (Ashlock et al). While there are multiple methods to perform a celiac plexus block, it involves a steep needle trajectory either posteriorly through the retroperitoneum or anteriorly through the abdominal wall close

Trial Locations (4)

19104

RECRUITING

Hospital of the University of Pennsylvania, Philadelphia

RECRUITING

Penn Presbyterian Medical Center, Philadelphia

19107

RECRUITING

Pennsylvania Hospital, Philadelphia

19143

RECRUITING

Hospital of the University of Pennsylvania -- Cedar Avenue, Philadelphia

All Listed Sponsors
lead

Abramson Cancer Center at Penn Medicine

OTHER

NCT07211386 - The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT) | Biotech Hunter | Biotech Hunter