25
Participants
Start Date
October 15, 2025
Primary Completion Date
May 15, 2027
Study Completion Date
June 15, 2027
Erector Spinae Plane Block
The abdominal viscera, from the stomach to midway through the sigmoid colon, derives its sensory innervation from afferent fibers that travel with, but are distinct from, the sympathetic nerve fibers from the 5th thoracic (T5) to the 2nd lumbar (L2) spinal levels (Moore et al). These fibers converge at the celiac plexus, located near the celiac artery and the aorta. From there, they bifurcate into the paravertebral sympathetic chain and subsequently ascend to the spinal cord and integrate into the central nervous system (Lohse et al). The celiac plexus block is an invasive procedure performed by an interventional anesthesiologist or palliative care specialist to lyse the celiac plexus and has been shown to reduce pain and opiate use in patients suffering from GI malignancy (Ashlock et al). While there are multiple methods to perform a celiac plexus block, it involves a steep needle trajectory either posteriorly through the retroperitoneum or anteriorly through the abdominal wall close
RECRUITING
Hospital of the University of Pennsylvania, Philadelphia
RECRUITING
Penn Presbyterian Medical Center, Philadelphia
RECRUITING
Pennsylvania Hospital, Philadelphia
RECRUITING
Hospital of the University of Pennsylvania -- Cedar Avenue, Philadelphia
Abramson Cancer Center at Penn Medicine
OTHER