Comparison Of Cytology And Molecular Screening For Detecting Cervical Reactive Cellular Changes In General Population

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

September 30, 2026

Conditions
Atypical Squamous Cell of Undetermined SignificanceASC-USAtypical Glandular Cells of Uncertain SignificanceAGUSCervical Intraepithelial Neoplasia (CIN)CIN 1CIN 2CIN 3Cervical Cancer
Interventions
PROCEDURE

Physical examination

Physical examination and interview for obtaining a medical record

OTHER

Liquid-based cytology

Screening test for cervical precursor lesions and/or cancer. LBC is a procedure in which a cervical smear is examined under the microscope.

OTHER

Molecular screening

The molecular screening detects three human biomarkers associated with cervical precursor lesions and/or cervical cancer. Biomarker detection is done by Western blot and ELISA in human sera.

OTHER

HPV DNA test

HPV DNA detection is performed using a cervical swab.

DIAGNOSTIC_TEST

Colposcopy

A diagnostic procedure to visually examine the cervix, vagina, and vulva with a colposcope.

DIAGNOSTIC_TEST

Histopathology

Is the definitive diagnosis of cervical precursor lesions and cervical cancer. It is the microscopic study of diseased cells and tissues stained with hematoxylin and eosin.

Trial Locations (1)

52105

Clinica Reina Madre Metepec, San Mateo Atenco

All Listed Sponsors
lead

Timser SAPI de CV

INDUSTRY