NCT07210684View on ClinicalTrials.gov

Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes

NARecruitingINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

August 6, 2025

Primary Completion Date

January 15, 2026

Study Completion Date

March 15, 2026

Conditions
Prediabetes
Interventions
DIETARY_SUPPLEMENT

Placebo 400 mg

Participants will receive 4 placebo capsules daily for 6 weeks. Each capsule contains 100 mg of microcrystalline cellulose, which serves as a inactive control substance.

DIETARY_SUPPLEMENT

Dihydroberberine（DHB）400 mg

Participants will receive 4 capsules of DHB (Dihydroberberine) 100 mg each, orally, once daily for 6 weeks. The total daily dose is 400 mg of DHB.

Trial Locations (1)

60101

RECRUITING

Merieux NutriSciences, Addison

All Listed Sponsors
collaborator

Biofortis, Merieux NutriSciences

INDUSTRY

lead

Nanjing Nutrabuilding Bio-tech Co., Ltd.

OTHER